4N73

Crystal structure of the ligand binding domain (LBD) of REV-ERB beta bound to Cobalt Protoporphyrin IX

Summary for 4N73

Entry DOI	10.2210/pdb4n73/pdb
Related	2V0V 3CQV 3N00
Descriptor	Nuclear receptor subfamily 1 group D member 2, PROTOPORPHYRIN IX CONTAINING CO (3 entities in total)
Functional Keywords	transcriptional regulator, nuclear receptor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q14995
Total number of polymer chains	1
Total formula weight	23074.37
Authors	Matta-Camacho, E.,Kojetin, D. (deposition date: 2013-10-14, release date: 2014-06-04, Last modification date: 2023-09-20)
Primary citation	Matta-Camacho, E.,Banerjee, S.,Hughes, T.S.,Solt, L.A.,Wang, Y.,Burris, T.P.,Kojetin, D.J. Structure of REV-ERB beta Ligand-binding Domain Bound to a Porphyrin Antagonist. J.Biol.Chem., 289:20054-20066, 2014 Cited by PubMed: 24872411 DOI: 10.1074/jbc.M113.545111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8662 Å)

Structure validation