4N73
Crystal structure of the ligand binding domain (LBD) of REV-ERB beta bound to Cobalt Protoporphyrin IX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor subfamily 1 group D member 2 | polymer | 199 | 22454.8 | 1 | UniProt (Q14995) Pfam (PF00104) | Homo sapiens (human) | Orphan nuclear hormone receptor BD73, Rev-erb-beta, V-erbA-related protein 1-related, EAR-1R |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING CO | non-polymer | 619.6 | 1 | Chemie (COH) | |||
| 3 | C (A) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 381 - 578 (UniProt: Q14995)
| PDB | External Database | Details |
|---|---|---|
| Gly 380 | - | expression tag |
| Met 386 | Leu 386 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22454.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 619.6 | |
| All* | Total formula weight | 23074.4 |
