3N00
Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A
Summary for 3N00
Entry DOI | 10.2210/pdb3n00/pdb |
Related | 2vov 3cqv |
Descriptor | Rev-erbA-alpha, Nuclear receptor corepressor 1 (3 entities in total) |
Functional Keywords | reverba ncorid1, anti-parallel b-sheet, transcription regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P20393 O75376 |
Total number of polymer chains | 2 |
Total formula weight | 30082.32 |
Authors | |
Primary citation | Phelan, C.A.,Gampe, R.T.,Lambert, M.H.,Parks, D.J.,Montana, V.,Bynum, J.,Broderick, T.M.,Hu, X.,Williams, S.P.,Nolte, R.T.,Lazar, M.A. Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction. Nat.Struct.Mol.Biol., 17:808-814, 2010 Cited by PubMed: 20581824DOI: 10.1038/nsmb.1860 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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