3N00

Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Rev-erbA-alpha	polymer	245	27612.5	1	UniProt (P20393) Pfam (PF00104)	Homo sapiens (human)	Nuclear receptor subfamily 1 group D member 1, V-erbA-related protein 1, EAR-1
2	B (B)	Nuclear receptor corepressor 1	polymer	21	2469.9	1	UniProt (O75376)	Homo sapiens	N-CoR1, N-CoR
3	C, D (A, B)	water	water		18.0	62	Chemie (HOH)

Sequence modifications

A: 281 - 422 (UniProt: P20393)

PDB	External Database	Details
Met 271	-	expression tag
Lys 272	-	expression tag
Lys 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
His 279	-	expression tag
Gly 280	-	expression tag

A: 423 - 614 (UniProt: P20393)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30082.3
All*	Total formula weight	30082.3

*Water molecules are not included.