6KS6
| TRiC at 0.2 mM ADP-AlFx, Conformation 1, 0.2-C1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Jin, M, Cong, Y. | 登録日 | 2019-08-23 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity. Proc.Natl.Acad.Sci.USA, 116, 2019
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6KVH
| The mutant crystal structure of endo-polygalacturonase (T284A) from Talaromyces leycettanus JCM 12802 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, endo-polygalacturonase | 著者 | Tu, T, Wang, Z, Luo, H, Yao, B. | 登録日 | 2019-09-04 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural Insights into the Mechanisms Underlying the Kinetic Stability of GH28 Endo-Polygalacturonase. J.Agric.Food Chem., 69, 2021
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7E7X
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7E8C
| SARS-CoV-2 S-6P in complex with 9 Fabs | 分子名称: | 368-2 H, 368-2 L, 604 H, ... | 著者 | Du, S, Xiao, J, Zhang, Z. | 登録日 | 2021-03-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
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7E8F
| SARS-CoV-2 NTD in complex with N9 Fab | 分子名称: | 368-2 H, 368-2 L, 604 H, ... | 著者 | Du, S, Xiao, J, Zhang, Z. | 登録日 | 2021-03-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
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7E86
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4Z8M
| Crystal structure of the MAVS-TRAF6 complex | 分子名称: | Peptide from Mitochondrial antiviral-signaling protein, TNF receptor-associated factor 6 | 著者 | Shi, Z.B, Zhou, Z. | 登録日 | 2015-04-09 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling J.Biol.Chem., 290, 2015
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6L31
| L1 protein of human papillomavirus 6 | 分子名称: | Major capsid protein L1 | 著者 | Li, S.W, Liu, X.L, Gu, Y. | 登録日 | 2019-10-07 | 公開日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
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7E39
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7E3B
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7E3C
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8QEO
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8QEN
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7E5R
| SARS-CoV-2 S trimer with three-antibody cocktail complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | 著者 | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | 登録日 | 2021-02-20 | 公開日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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7BVH
| Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose | 分子名称: | CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, ... | 著者 | Zhao, Y, Zhang, L, Wu, L.J, Wang, Q, Li, J, Besra, G.S, Rao, Z.H. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
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7BVF
| Cryo-EM structure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol | 分子名称: | CALCIUM ION, CARDIOLIPIN, Ethambutol, ... | 著者 | Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
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8U1F
| FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10 | 分子名称: | Fibroblast growth factor receptor 2, GLYCEROL, N-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide, ... | 著者 | Valverde, R, Foster, L. | 登録日 | 2023-08-31 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2. Proc.Natl.Acad.Sci.USA, 121, 2024
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7E5S
| SARS-CoV-2 S trimer with four-antibody cocktail complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | 著者 | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | 登録日 | 2021-02-20 | 公開日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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5C6D
| Crystal structure of USP7 in complex with UHRF1 | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Zhang, Z.-M, Song, J. | 登録日 | 2015-06-22 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Rep, 12, 2015
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8JBJ
| Crystal structure of anti-PVRIG Fab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Li, X.L, Song, J. | 登録日 | 2023-05-09 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity. Mabs, 15, 2023
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6MPH
| Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ... | 著者 | Acharya, P, Xu, K, Kwong, P.D. | 登録日 | 2018-10-06 | 公開日 | 2019-07-24 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
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4MZ9
| Revised structure of E. coli SSB | 分子名称: | Single-stranded DNA-binding protein | 著者 | Oakley, A.J. | 登録日 | 2013-09-29 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Intramolecular binding mode of the C-terminus of Escherichia coli single-stranded DNA binding protein determined by nuclear magnetic resonance spectroscopy. Nucleic Acids Res., 42, 2014
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6MX8
| Crystal structure of anaplastic lymphoma kinase (ALK) bound by Brigatinib | 分子名称: | 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor | 著者 | Dougan, D.R, Zhou, T. | 登録日 | 2018-10-30 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase. J. Med. Chem., 59, 2016
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6KDV
| Crystal structure of TtCas1-DNA complex | 分子名称: | CRISPR-associated endonuclease Cas1 2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*GP*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*AP*GP*CP*AP*TP*CP*GP*AP*CP*TP*C)-3') | 著者 | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | 登録日 | 2019-07-02 | 公開日 | 2019-12-18 | 最終更新日 | 2020-05-06 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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5CH8
| Crystal structure of MDLA N225Q mutant form Penicillium cyclopium | 分子名称: | CHLORIDE ION, GLYCEROL, Mono- and diacylglycerol lipase, ... | 著者 | Xu, J, Xu, H, Hou, S, Liu, J. | 登録日 | 2015-07-10 | 公開日 | 2016-04-20 | 最終更新日 | 2017-09-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Lipase-Driven Epoxidation Is A Two-Stage Synergistic Process ChemistrySelect, 4, 2016
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