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TPX2 residues 7-20 fused to Aurora A residues 116-389 dephosphorylated, and CoAlated on C290
分子名称:	COENZYME A, TPX2 fragment - Aurora A kinase domain fusion
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-06-26
公開日	2020-08-05
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

8SMK

hPAD4 bound to Activating Fab hA362
分子名称:	Activating Fab 362 heavy chain, Activating Fab 362 light chain, CALCIUM ION, ...
著者	Maker, A, Verba, K.A.
登録日	2023-04-26
公開日	2024-03-06
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (3.5 Å)
主引用文献	Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4. Nat.Chem.Biol., 20, 2024

8SML

hPAD4 bound to inhibitory Fab hI365
分子名称:	CALCIUM ION, Fab hI365 heavy chain, Fab hI365 light chain, ...
著者	Maker, A, Verba, K.A.
登録日	2023-04-26
公開日	2024-03-06
最終更新日	2024-06-12
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4. Nat.Chem.Biol., 20, 2024

3R6G

Crystal structure of active caspase-2 bound with Ac-VDVAD-CHO
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)VDVAD-CHO
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-21
公開日	2011-07-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.07 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

3R7S

Crystal Structure of Apo Caspase2
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-22
公開日	2011-07-27
最終更新日	2019-07-17
実験手法	X-RAY DIFFRACTION (2.252 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

3R5J

Crystal structure of active caspase-2 bound with Ac-ADVAD-CHO
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)ADVAD-CHO
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-18
公開日	2011-07-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (1.77 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

3R6L

Caspase-2 T380A bound with Ac-VDVAD-CHO
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)VDVAD-CHO
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-21
公開日	2011-07-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

3R7B

Caspase-2 bound to one copy of Ac-DVAD-CHO
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)DVAD-CHO
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-22
公開日	2011-07-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

3R7N

Caspase-2 bound with two copies of Ac-DVAD-CHO
分子名称:	Caspase-2 subunit p12, Caspase-2 subunit p18, Peptide Inhibitor (ACE)DVAD-CHO
著者	Tang, Y, Wells, J, Arkin, M.
登録日	2011-03-22
公開日	2011-07-27
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.33 Å)
主引用文献	Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J.Biol.Chem., 286, 2011

1A22

HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR
分子名称:	GROWTH HORMONE, GROWTH HORMONE RECEPTOR
著者	De Vos, A.M, Ultsch, M.
登録日	1998-01-15
公開日	1998-04-29
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277, 1998

1CA0

BOVINE CHYMOTRYPSIN COMPLEXED TO APPI
分子名称:	BOVINE CHYMOTRYPSIN, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR
著者	Scheidig, A.J, Kossiakoff, A.A.
登録日	1997-01-23
公開日	1997-07-23
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci., 6, 1997

1CBW

BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI
分子名称:	BOVINE CHYMOTRYPSIN, BPTI, SULFATE ION
著者	Hynes, T.R, Scheidig, A.J, Kossiakoff, A.A.
登録日	1996-12-22
公開日	1997-07-23
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci., 6, 1997

6VO4

Crystal Structure Analysis of BFL1
分子名称:	Bcl-2-related protein A1
著者	Seo, H.-S, Dhe-Paganon, S.
登録日	2020-01-29
公開日	2020-06-03
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.74 Å)
主引用文献	Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chem Biol, 27, 2020

6VPG

TPX2 residues 7-20 fused to Aurora A residues 116-389 in complex with AMP-PNP
分子名称:	CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.64 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

6VPM

TPX2 residues 7-20 fused to Aurora A residues 116-389 with C290 disulfide bonded to compound 8-34, and in complex with AMP-PNP
分子名称:	ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MALONIC ACID, ...
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.58 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

6VPI

TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + D256N + C319V triple mutant disulfide homodimer in complex with AMP-PNP
分子名称:	MAGNESIUM ION, MALONIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

6VPL

TPX2 residues 7-20 fused to Aurora A residues 116-389 with C290 disulfide bonded to compound 7-80, and in complex with AMP-PNP
分子名称:	GLYCEROL, MAGNESIUM ION, MALONIC ACID, ...
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.86 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

6VPJ

TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + C319V double mutant dephosphorylated, and in complex with AMP-PNP
分子名称:	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TPX2 fragment - Aurora A kinase domain fusion, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

6VPH

TPX2 residues 7-20 fused to Aurora A residues 116-389 modified with cacodylate and in complex with AMP-PNP
分子名称:	CHLORIDE ION, DITHIANE DIOL, GLYCEROL, ...
著者	Lim, D.C, Yaffe, M.B.
登録日	2020-02-03
公開日	2020-08-05
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.14 Å)
主引用文献	Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020

2ST1

THE THREE-DIMENSIONAL STRUCTURE OF BACILLUS AMYLOLIQUEFACIENS SUBTILISIN AT 1.8 ANGSTROMS AND AN ANALYSIS OF THE STRUCTURAL CONSEQUENCES OF PEROXIDE INACTIVATION
分子名称:	CALCIUM ION, SUBTILISIN BPN', SULFATE ION
著者	Bott, R.
登録日	1990-05-11
公開日	1991-07-15
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation. J.Biol.Chem., 263, 1988

1ZDB

PHAGE-SELECTED MINI PROTEIN A DOMAIN, Z38, NMR, MINIMIZED MEAN STRUCTURE
分子名称:	MINI PROTEIN A DOMAIN, Z38
著者	Starovasnik, M.A.
登録日	1997-07-09
公開日	1997-09-17
最終更新日	2024-05-22
実験手法	SOLUTION NMR
主引用文献	Structural mimicry of a native protein by a minimized binding domain. Proc.Natl.Acad.Sci.USA, 94, 1997

1ZDD

DISULFIDE-STABILIZED MINI PROTEIN A DOMAIN, Z34C, NMR, MINIMIZED MEAN STRUCTURE
分子名称:	STABLE MINI PROTEIN A DOMAIN, Z34C
著者	Starovasnik, M.A.
登録日	1997-07-09
公開日	1997-09-17
最終更新日	2022-03-02
実験手法	SOLUTION NMR
主引用文献	Structural mimicry of a native protein by a minimized binding domain. Proc.Natl.Acad.Sci.USA, 94, 1997

1ZDC

DISULFIDE-STABILIZED MINI PROTEIN A DOMAIN, Z34C, NMR, 24 STRUCTURES
分子名称:	STABLE MINI PROTEIN A DOMAIN, Z34C
著者	Starovasnik, M.A.
登録日	1997-07-09
公開日	1997-09-17
最終更新日	2022-03-02
実験手法	SOLUTION NMR
主引用文献	Structural mimicry of a native protein by a minimized binding domain. Proc.Natl.Acad.Sci.USA, 94, 1997

1VPF

STRUCTURE OF HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR
分子名称:	VASCULAR ENDOTHELIAL GROWTH FACTOR
著者	Muller, Y.A, De Vos, A.M.
登録日	1997-04-08
公開日	1998-04-08
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc.Natl.Acad.Sci.USA, 94, 1997

1ZDA

PHAGE-SELECTED MINI PROTEIN A DOMAIN, Z38, NMR, 24 STRUCTURES
分子名称:	MINI PROTEIN A DOMAIN, Z38
著者	Starovasnik, M.A.
登録日	1997-07-09
公開日	1997-09-17
最終更新日	2024-05-22
実験手法	SOLUTION NMR
主引用文献	Structural mimicry of a native protein by a minimized binding domain. Proc.Natl.Acad.Sci.USA, 94, 1997

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全ヒット件数:	239
表示件数:	25
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