3R6L

Caspase-2 T380A bound with Ac-VDVAD-CHO

Summary for 3R6L

• Entry DOI: 10.2210/pdb3r6l/pdb
• Related: 3R5J 3R6G 3R7B 3R7N 3R7S
• Related PRD ID: PRD_001048
• Descriptor: Caspase-2 subunit p18, Caspase-2 subunit p12, Peptide Inhibitor (ACE)VDVAD-CHO, ... (4 entities in total)
• Functional Keywords: hydrolase, apoptosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 63024.13

Authors

Tang, Y.,Wells, J.,Arkin, M. (deposition date: 2011-03-21, release date: 2011-07-27, Last modification date: 2012-12-12)

• Primary citation: Tang, Y.,Wells, J.A.,Arkin, M.R.; Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.; J.Biol.Chem., 286:34147-34154, 2011; PubMed: 21828056; DOI: 10.1074/jbc.M111.247627

Experimental method

X-RAY DIFFRACTION (1.9 Å)