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4W9Y
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BU of 4w9y by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a glutamyl sulfamide inhibitor CJC47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Pavlicek, J, Barinka, C.
登録日2014-08-28
公開日2015-09-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors.
J.Chem.Inf.Model., 2024
2HVQ
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BU of 2hvq by Molmil
Structure of Adenylated full-length T4 RNA Ligase 2
分子名称: Hypothetical 37.6 kDa protein in Gp24-hoc intergenic region, MAGNESIUM ION
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVS
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BU of 2hvs by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 2'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVR
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BU of 2hvr by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
1CKN
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BU of 1ckn by Molmil
STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, MRNA CAPPING ENZYME, ...
著者Hakansson, K, Doherty, A.J, Wigley, D.B.
登録日1997-04-20
公開日1997-07-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
1CKM
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BU of 1ckm by Molmil
STRUCTURE OF TWO DIFFERENT CONFORMATIONS OF MRNA CAPPING ENZYME IN COMPLEX WITH GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME
著者Hakansson, K, Doherty, A.J, Wigley, D.B.
登録日1997-04-20
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
6W08
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BU of 6w08 by Molmil
Crystal Structure of Motility Associated Killing Factor E from Vibrio cholerae
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ...
著者Kim, Y, Jedrzejczak, R, Joachimiak, G, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-02-29
公開日2020-03-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
J.Bacteriol., 204, 2022
6W1W
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BU of 6w1w by Molmil
Crystal Structure of Motility Associated Killing Factor B from Vibrio cholerae
分子名称: 1,2-ETHANEDIOL, motility-associated killing factor MakB
著者Kim, Y, Welk, L, Jedrzejczak, R, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-03-04
公開日2020-03-25
最終更新日2022-07-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
J.Bacteriol., 204, 2022
1CKO
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BU of 1cko by Molmil
STRUCTURE OF MRNA CAPPING ENZYME IN COMPLEX WITH THE CAP ANALOG GPPPG
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME, ZINC ION
著者Hakansson, K, Wigley, D.B.
登録日1997-09-06
公開日1998-01-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Proc.Natl.Acad.Sci.USA, 95, 1998
4PZ6
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BU of 4pz6 by Molmil
PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD
分子名称: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha
著者Doamekpor, S.K, Lima, C.D.
登録日2014-03-28
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
6O3Z
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BU of 6o3z by Molmil
Crystal structure of RORgt with 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl)benzamide (compound 1)
分子名称: 1,2-ETHANEDIOL, 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl)benzamide, RAR-related orphan receptor C isoform a variant
著者Min, X, Wang, Z.
登録日2019-02-27
公開日2020-03-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable ROR gamma t Inverse Agonists.
Acs Med.Chem.Lett., 11, 2020
4S0H
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BU of 4s0h by Molmil
TBX5 DB, NKX2.5 HD, ANF DNA Complex
分子名称: 5'-D(*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP*TP*GP*AP*AP*GP*TP*GP*G)-3', Homeobox protein Nkx-2.5, ...
著者Pradhan, L.
登録日2014-12-31
公開日2015-12-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.817 Å)
主引用文献Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
6O3T
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BU of 6o3t by Molmil
Structural basis of FOXC2 and DNA interactions
分子名称: DNA (5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein C2
著者Nam, H.-J, Li, S.
登録日2019-02-27
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Crystal Structure of FOXC2 in Complex with DNA Target.
Acs Omega, 4, 2019
6RKJ
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BU of 6rkj by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinooctaose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-04-30
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RKH
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BU of 6rkh by Molmil
The crystal structure of AbnE (Selenium derivative), an arabino-oligosaccharide binding protein, in complex with arabinohexaose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose-(1-5)-alpha-L-arabinofuranose
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-04-30
公開日2020-04-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.471 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RJY
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BU of 6rjy by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinobiose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arabino-oligosaccharids-binding protein, CALCIUM ION, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-04-29
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.621 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RKL
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BU of 6rkl by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinoheptaose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-04-30
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RL1
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BU of 6rl1 by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotriose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-05-01
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RKX
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BU of 6rkx by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinopentaose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-04-30
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.094 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
6RL2
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BU of 6rl2 by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotetraose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-05-01
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
5BQD
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BU of 5bqd by Molmil
Crystal Structure of TBX5 (1-239) Dimer
分子名称: MAGNESIUM ION, T-box transcription factor TBX5
著者Pradhan, L, Gopal, S, Patel, A, Kasahara, H, Nam, H.J.
登録日2015-05-28
公開日2016-03-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.583 Å)
主引用文献Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.
Biochemistry, 55, 2016
6RTI
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BU of 6rti by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g
分子名称: (2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Motlova, L, Kolenko, P, Barinka, C.
登録日2019-05-24
公開日2020-06-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.
Nucleic Acids Res., 48, 2020
4XQ0
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BU of 4xq0 by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to beryllium fluoride
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAETHYLENE GLYCOL
著者Ghosh, A, Lima, C.D.
登録日2015-01-18
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
4XPZ
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BU of 4xpz by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to aluminum fluoride
分子名称: ALUMINUM FLUORIDE, MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, ...
著者Ghosh, A, Lima, C.D.
登録日2015-01-18
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
6K0T
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BU of 6k0t by Molmil
Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-17
分子名称: 3-[(1~{E})-1-[8-[(8-chloranyl-2-cyclopropyl-imidazo[1,2-a]pyridin-3-yl)methyl]-3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene]ethyl]-4~{H}-1,2,4-oxadiazol-5-one, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
著者Suzuki, M, Yamamoto, K, Takahashi, Y, Saito, J.
登録日2019-05-07
公開日2019-10-30
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold.
Bioorg.Med.Chem., 27, 2019

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