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7BRO
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BU of 7bro by Molmil
Crystal structure of the 2019-nCoV main protease
分子名称: 3C-like proteinase
著者Fu, L.F.
登録日2020-03-29
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
5GMV
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BU of 5gmv by Molmil
LC3B-FUNDC1 complex
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1
著者Lv, M, Wang, C, Li, F.
登録日2016-07-17
公開日2017-03-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
Protein Cell, 8, 2017
7BRP
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BU of 7brp by Molmil
Crystal structure of the 2019-nCoV main protease complexed with Boceprevir
分子名称: 3C-like proteinase, boceprevir (bound form)
著者Fu, L.F.
登録日2020-03-29
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease.
Nat Commun, 11, 2020
7MEJ
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BU of 7mej by Molmil
CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb36
分子名称: Nanobody Nb21, Nanobody Nb36, Spike protein S1
著者Huang, W, Taylor, D.J.
登録日2021-04-06
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7MDW
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BU of 7mdw by Molmil
CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb105
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nanobody Nb105, ...
著者Huang, W, Taylor, D.J.
登録日2021-04-06
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7ME7
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BU of 7me7 by Molmil
CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb17 and Nb105
分子名称: Nanobody Nb105, Nanobody Nb17, Spike protein S1
著者Huang, W, Taylor, D.J.
登録日2021-04-06
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
6KI6
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BU of 6ki6 by Molmil
Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region
分子名称: B-cell lymphoma/leukemia 11A, DNA (5'-D(*AP*TP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*A)-3'), ...
著者Li, F.D, Yang, Y, Shi, Y.Y.
登録日2019-07-17
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the recognition of gamma-globin gene promoter by BCL11A.
Cell Res., 29, 2019
7LD0
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BU of 7ld0 by Molmil
Cryo-EM structure of ligand-free Human SARM1
分子名称: NAD(+) hydrolase SARM1
著者Nanson, J.D, Gu, W, Luo, Z, Jia, X, Landsberg, M.J, Kobe, B, Ve, T.
登録日2021-01-12
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
7LCY
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BU of 7lcy by Molmil
Crystal structure of the ligand-free ARM domain from Drosophila SARM1
分子名称: Isoform B of NAD(+) hydrolase sarm1
著者Gu, W, Nanson, J.D, Luo, Z, McGuinness, H.Y, Manik, M.K, Jia, X, Ve, T, Kobe, B.
登録日2021-01-12
公開日2021-03-10
最終更新日2021-04-21
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
7LCZ
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BU of 7lcz by Molmil
Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN
分子名称: 1,2-ETHANEDIOL, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Isoform B of NAD(+) hydrolase sarm1, ...
著者Gu, W, Nanson, J.D, Luo, Z, Jia, X, Manik, M.K, Ve, T, Kobe, B.
登録日2021-01-12
公開日2021-03-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
5H5N
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BU of 5h5n by Molmil
The crystal structure of the NS1 (H17N10) RNA-binding domain
分子名称: Non-structural protein 1
著者Zhao, X, Qi, J, Xiao, H, Gao, G.F.
登録日2016-11-08
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The NS1 gene from bat-derived influenza-like virus H17N10 can be rescued in influenza A PR8 backbone
J.Gen.Virol., 97, 2016
4M57
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BU of 4m57 by Molmil
Crystal structure of the pentatricopeptide repeat protein PPR10 from maize
分子名称: Chloroplast pentatricopeptide repeat protein 10
著者Yin, P, Li, Q, Yan, C, Liu, Y, Yan, N.
登録日2013-08-08
公開日2013-10-30
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
6A4M
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BU of 6a4m by Molmil
Structure of urate oxidase from Bacillus subtilis 168
分子名称: GLYCEROL, Uric acid degradation bifunctional protein PucL
著者Jiang, Y.Y.
登録日2018-06-20
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Urate Oxidase from Bacillus Subtilis 168
Crystallography Reports, 64, 2019
6AKJ
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BU of 6akj by Molmil
The crystal structure of EMC complex
分子名称: Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein, SULFATE ION
著者Li, F.
登録日2018-09-01
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing.
Nat Commun, 10, 2019
8X2L
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BU of 8x2l by Molmil
Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
著者Chen, L, Liu, X.
登録日2023-11-09
公開日2024-01-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
著者Chen, L, Liu, X.
登録日2023-09-18
公開日2024-01-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024
8YLC
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BU of 8ylc by Molmil
The crystal structure of PDE4D with Amentoflavone
分子名称: 3',5'-cyclic-AMP phosphodiesterase 4D, 8-[5-[5,7-bis(oxidanyl)-4-oxidanylidene-chromen-2-yl]-2-oxidanyl-phenyl]-2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one, MAGNESIUM ION, ...
著者Huang, Y.-Y, Luo, H.-B.
登録日2024-03-06
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.30003715 Å)
主引用文献Discovery of amentoflavone as a natural PDE4 inhibitor with anti-fibrotic effects
Chin.Chem.Lett., 2024
8H56
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BU of 8h56 by Molmil
Crystal structure of Rep' of porcine circovirus type 2
分子名称: Isoform Rep' of Replication-associated protein
著者Guan, S.Y, Song, Y.F.
登録日2022-10-12
公開日2023-05-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure of the dimerized of porcine circovirus type II replication-related protein Rep'.
Proteins, 91, 2023
2LN0
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BU of 2ln0 by Molmil
Structure of MOZ
分子名称: Histone acetyltransferase KAT6A, ZINC ION
著者Qiu, Y.
登録日2011-12-15
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription.
Genes Dev., 26, 2012
7BSD
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BU of 7bsd by Molmil
Complex structure of 1G5.3 Fab bound to ZIKV NS1c
分子名称: 1G5.3 Fab Heavy Chain, 1G5.3 Fab Light Chain, NS1C
著者Song, H, Qi, J, Gao, F.G.
登録日2020-03-30
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献A broadly protective antibody that targets the flavivirus NS1 protein.
Science, 371, 2021
7BSC
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BU of 7bsc by Molmil
Complex structure of 1G5.3 Fab bound to DENV2 NS1c
分子名称: 1G5.3 Fab Heavy Chain, 1G5.3 Fab Light Chain, Non-structural protein 1
著者Song, H, Qi, J, Gao, F.G.
登録日2020-03-30
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A broadly protective antibody that targets the flavivirus NS1 protein.
Science, 371, 2021
4ZY3
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BU of 4zy3 by Molmil
Crystal Structure of Keap1 in Complex with a small chemical compound, K67
分子名称: FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide)
著者Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M.
登録日2015-05-21
公開日2016-05-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Nat Commun, 7, 2016
6LJJ
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BU of 6ljj by Molmil
Swine dUTPase in complex with alpha,beta-iminodUTP and magnesium ion
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, ...
著者Liang, R, Peng, G.Q.
登録日2019-12-16
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development.
J.Biol.Chem., 296, 2020
2L89
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BU of 2l89 by Molmil
Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
分子名称: PWWP domain-containing protein 1
著者Qiu, Y, Zhang, J, Zhang, W.
登録日2011-01-07
公開日2011-12-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
Biochem.J., 2011
1M5Z
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BU of 1m5z by Molmil
The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
分子名称: AMPA receptor interacting protein
著者Feng, W, Fan, J, Jiang, M, Shi, Y, Zhang, M.
登録日2002-07-11
公開日2002-11-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
J.Biol.Chem., 277, 2002

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