7BRO

Crystal structure of the 2019-nCoV main protease

Summary for 7BRO

Entry DOI	10.2210/pdb7bro/pdb
Descriptor	3C-like proteinase (2 entities in total)
Functional Keywords	2019-ncov main protease, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	1
Total formula weight	33882.60
Authors	Fu, L.F. (deposition date: 2020-03-29, release date: 2020-05-13, Last modification date: 2023-11-29)
Primary citation	Fu, L.,Ye, F.,Feng, Y.,Yu, F.,Wang, Q.,Wu, Y.,Zhao, C.,Sun, H.,Huang, B.,Niu, P.,Song, H.,Shi, Y.,Li, X.,Tan, W.,Qi, J.,Gao, G.F. Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11:4417-4417, 2020 Cited by PubMed: 32887884 DOI: 10.1038/s41467-020-18233-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation