8X2L

Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH

Summary for 8X2L

• Entry DOI: 10.2210/pdb8x2l/pdb
• Related: 8GZ3
• EMDB information: 38016
• Descriptor: Cytochrome b-245 light chain, Cytochrome b-245 heavy chain, 7D5 Fab heavy chain, ... (10 entities in total)
• Functional Keywords: nox2, p22, cyba, cybb, tp1170, nox, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 143332.05

Authors

Chen, L.,Liu, X. (deposition date: 2023-11-09, release date: 2024-01-24, Last modification date: 2024-03-20)

• Primary citation: Liu, X.,Shi, Y.,Liu, R.,Song, K.,Chen, L.; Structure of human phagocyte NADPH oxidase in the activated state.; Nature, 627:189-195, 2024; PubMed: 38355798; DOI: 10.1038/s41586-024-07056-1

Experimental method

ELECTRON MICROSCOPY (2.99 Å)