8X2L
Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cytochrome b-245 light chain | polymer | 195 | 21005.4 | 1 | UniProt (P13498) Pfam (PF05038) In PDB | Homo sapiens (human) | |
| 2 | B | Cytochrome b-245 heavy chain | polymer | 570 | 65412.7 | 1 | UniProt (P04839) Pfam (PF01794) Pfam (PF08022) Pfam (PF08030) In PDB | Homo sapiens (human) | |
| 3 | H | 7D5 Fab heavy chain | polymer | 251 | 27603.9 | 1 | Mus musculus | ||
| 4 | L | 7D5 Fab light chain | polymer | 236 | 26238.2 | 1 | Mus musculus | ||
| 5 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 7 | B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 8 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 9 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 10 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 195 (UniProt: P13498)
| PDB | External Database | Details |
|---|---|---|
| Ala 174 | Val 174 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140260.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2485.2 | |
| All* | Total formula weight | 143332.0 |
