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3KXI
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BU of 3kxi by Molmil
crystal structure of SsGBP and GDP complex
分子名称: GTP-binding protein (HflX), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Huang, B, Li, X, Zhang, X.C, Rao, Z.
登録日2009-12-03
公開日2010-05-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
3KXK
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BU of 3kxk by Molmil
Crystal structure of SsGBP mutation variant G235P
分子名称: GTP-binding protein (HflX)
著者Huang, B, Li, X, Zhang, X.C, Rao, Z.
登録日2009-12-03
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
6E7P
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BU of 6e7p by Molmil
cryo-EM structure of human TRPML1 with PI35P2
分子名称: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Y
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BU of 6e7y by Molmil
cryo-EM structure of human TRPML1 with PI45P2
分子名称: Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Z
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BU of 6e7z by Molmil
cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2
分子名称: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
5JYY
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BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
著者Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
登録日2016-05-15
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
7P5R
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BU of 7p5r by Molmil
Racemic protein crystal structure of lacticin Q from Lactococcus lactis
分子名称: D-Lacticin Q, FORMIC ACID, Lacticin Q
著者Lander, A.J, Li, X, Baumann, P, Rizkallah, P, Luk, L.Y.P, Jin, Y.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography.
Commun Chem, 6, 2023
7TBW
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BU of 7tbw by Molmil
The structure of ATP-bound ABCA1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TC0
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BU of 7tc0 by Molmil
The structure of human ABCA1 in digitonin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBZ
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BU of 7tbz by Molmil
The structure of ABCA1 Y482C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBY
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BU of 7tby by Molmil
The structure of human ABCA1 in nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
5XRA
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BU of 5xra by Molmil
Crystal structure of the human CB1 in complex with agonist AM11542
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (6aR,10aR)-3-(8-bromanyl-2-methyl-octan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol, CHOLESTEROL, ...
著者Hua, T, Vemuri, K, Nikas, P.S, Laprairie, R.B, Wu, Y, Qu, L, Pu, M, Korde, A, Shan, J, Ho, J.H, Han, G.W, Ding, K, Li, X, Liu, H, Hanson, M.A, Zhao, S, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J.
登録日2017-06-08
公開日2017-07-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of agonist-bound human cannabinoid receptor CB1
Nature, 547, 2017
7RR5
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BU of 7rr5 by Molmil
Structure of ribosomal complex bound with Rbg1/Tma46
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ...
著者Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H.
登録日2021-08-09
公開日2021-11-10
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
6WEK
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BU of 6wek by Molmil
Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEL
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BU of 6wel by Molmil
Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEJ
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BU of 6wej by Molmil
Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
4RM0
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BU of 4rm0 by Molmil
Crystal structure of Norovirus OIF P domain in complex with Lewis a trisaccharide
分子名称: Capsid protein, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
登録日2014-10-18
公開日2015-06-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4RLZ
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BU of 4rlz by Molmil
Crystal structure of Norovirus OIF P domain
分子名称: Capsid protein, GLYCEROL
著者Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
登録日2014-10-18
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
分子名称: GAMMA-SECRETASE, LYSOZYME
著者Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
登録日2015-04-03
公開日2015-06-10
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
6LH8
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BU of 6lh8 by Molmil
Structure of aerolysin-like protein (Bombina maxima)
分子名称: aerolysin-like protein
著者Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
登録日2019-12-07
公開日2020-06-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
6LHZ
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BU of 6lhz by Molmil
Structure of aerolysin-like protein (Bombina maxima)
分子名称: aerolysin-like protein
著者Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
登録日2019-12-10
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
5ADY
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BU of 5ady by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with HflX
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
著者Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
登録日2015-08-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
4I8B
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BU of 4i8b by Molmil
Crystal Structure of Thioredoxin from Schistosoma Japonicum
分子名称: Thioredoxin
著者Wu, Q, Peng, Y, Zhao, J, Li, X, Fan, X, Zhou, X, Chen, J, Luo, Z, Shi, D.
登録日2012-12-03
公開日2013-12-04
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Expression, characterization and crystal structure of thioredoxin from Schistosoma japonicum.
Parasitology, 142, 2015
3AQQ
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BU of 3aqq by Molmil
Crystal structure of human CRHSP-24
分子名称: Calcium-regulated heat stable protein 1
著者Hou, H, Wang, F, Zhang, W, Wang, D, Li, X, Bartlam, M, Yao, X, Rao, Z.
登録日2010-11-17
公開日2010-12-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies
To be Published
8WYI
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BU of 8wyi by Molmil
T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC
分子名称: Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ...
著者Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
登録日2023-10-31
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024

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