4O9F
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4O9L
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4N6F
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![BU of 4n6f by Molmil](/molmil-images/mine/4n6f) | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | 分子名称: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | 登録日 | 2013-10-11 | 公開日 | 2014-05-14 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
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4N6E
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![BU of 4n6e by Molmil](/molmil-images/mine/4n6e) | Crystal structure of Amycolatopsis orientalis BexX/CysO complex | 分子名称: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | 登録日 | 2013-10-11 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
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4OA7
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![BU of 4oa7 by Molmil](/molmil-images/mine/4oa7) | Crystal structure of Tankyrase1 in complex with IWR1 | 分子名称: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | 著者 | Zhang, X, He, H. | 登録日 | 2014-01-03 | 公開日 | 2015-01-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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7LCI
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![BU of 7lci by Molmil](/molmil-images/mine/7lci) | PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex | 分子名称: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Johnson, R.M, Drulyte, I, Yu, L, Kotecha, A, Danev, R, Wootten, D, Zhang, X, Sexton, P.M. | 登録日 | 2021-01-11 | 公開日 | 2021-01-20 | 最終更新日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29, 2021
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7LCJ
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![BU of 7lcj by Molmil](/molmil-images/mine/7lcj) | PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex | 分子名称: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor | 著者 | Belousoff, M.J, Johnson, R.M, Drulyte, I, Yu, L, Kotecha, A, Danev, R, Wootten, D, Zhang, X, Sexton, P.M. | 登録日 | 2021-01-11 | 公開日 | 2021-01-20 | 最終更新日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29, 2021
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7LCK
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![BU of 7lck by Molmil](/molmil-images/mine/7lck) | PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R) | 分子名称: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor | 著者 | Belousoff, M.J, Johnson, R.M, Drulyte, I, Yu, L, Kotecha, A, Danev, R, Wootten, D, Zhang, X, Sexton, P.M. | 登録日 | 2021-01-11 | 公開日 | 2021-01-20 | 最終更新日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29, 2021
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8XJK
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![BU of 8xjk by Molmil](/molmil-images/mine/8xjk) | Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex | 分子名称: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | 登録日 | 2023-12-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJO
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![BU of 8xjo by Molmil](/molmil-images/mine/8xjo) | U46619 bound Thromboxane A2 receptor-Gq Protein Complex | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | 登録日 | 2023-12-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJN
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![BU of 8xjn by Molmil](/molmil-images/mine/8xjn) | Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex | 分子名称: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | 登録日 | 2023-12-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJL
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![BU of 8xjl by Molmil](/molmil-images/mine/8xjl) | PGF2-alpha bound Prostaglandin F2-alpha receptor-Gq Protein Complex | 分子名称: | (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | 登録日 | 2023-12-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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2Z41
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![BU of 2z41 by Molmil](/molmil-images/mine/2z41) | Crystal Structure Analysis of the Ski2-type RNA helicase | 分子名称: | MAGNESIUM ION, putative ski2-type helicase | 著者 | Nakashima, T, Zhang, X, Kakuta, Y, Yao, M, Tanaka, I, Kimura, M. | 登録日 | 2007-06-12 | 公開日 | 2008-04-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | 主引用文献 | Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3 Protein Sci., 17, 2008
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5Y14
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![BU of 5y14 by Molmil](/molmil-images/mine/5y14) | Crystal structure of LP-40/N44 | 分子名称: | LP-40, N44 | 著者 | Zhang, X, Wang, X, He, Y. | 登録日 | 2017-07-19 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | 主引用文献 | Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition J. Virol., 91, 2017
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5Y9W
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![BU of 5y9w by Molmil](/molmil-images/mine/5y9w) | Crystal 1 for AtLURE1.2-AtPRK6LRR | 分子名称: | Pollen receptor-like kinase 6, Protein LURE 1.2, SULFATE ION | 著者 | Chai, J, Zhang, X. | 登録日 | 2017-08-28 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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5YC0
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![BU of 5yc0 by Molmil](/molmil-images/mine/5yc0) | Crystal structure of LP-46/N44 | 分子名称: | Envelope glycoprotein, LP-46 | 著者 | Zhang, X, Wang, X, He, Y. | 登録日 | 2017-09-05 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus J. Biol. Chem., 293, 2018
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5YAH
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![BU of 5yah by Molmil](/molmil-images/mine/5yah) | Crystal 2 for AtLURE1.2-AtPRK6LRR | 分子名称: | Pollen receptor-like kinase 6, Protein LURE 1.2 | 著者 | Chai, J, Zhang, X. | 登録日 | 2017-08-31 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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6X1A
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![BU of 6x1a by Molmil](/molmil-images/mine/6x1a) | Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | 分子名称: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Zhang, X, Danev, R. | 登録日 | 2020-05-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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6X19
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![BU of 6x19 by Molmil](/molmil-images/mine/6x19) | Non peptide agonist CHU-128, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | 分子名称: | 3-{(1S)-1-[5-(2,2-dimethylmorpholin-4-yl)-2-{(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carbonyl}-1H-indol-1-yl]butyl}-1,2,4-oxadiazol-5(4H)-one, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Zhang, X, Danev, R. | 登録日 | 2020-05-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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6X18
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![BU of 6x18 by Molmil](/molmil-images/mine/6x18) | GLP-1 peptide hormone bound to Glucagon-Like peptide-1 (GLP-1) Receptor | 分子名称: | Glucagon, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Belousoff, M.J, Zhang, X, Danev, R. | 登録日 | 2020-05-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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5XWY
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![BU of 5xwy by Molmil](/molmil-images/mine/5xwy) | Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex | 分子名称: | A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) | 著者 | Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M. | 登録日 | 2017-06-30 | 公開日 | 2017-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a. Cell, 170, 2017
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5ZIW
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5ZKZ
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5ZII
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5XUR
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![BU of 5xur by Molmil](/molmil-images/mine/5xur) | Crystal Structure of Rv2466c C22S Mutant | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Thioredoxin-like reductase Rv2466c | 著者 | Zhang, X, Li, H. | 登録日 | 2017-06-25 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | 主引用文献 | Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis, 4, 2018
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