7LCI
PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex
Summary for 7LCI
Entry DOI | 10.2210/pdb7lci/pdb |
Related | 6X1A |
EMDB information | 23274 |
Descriptor | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, small molecule agonist, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 146792.65 |
Authors | Belousoff, M.J.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Zhang, X.,Sexton, P.M. (deposition date: 2021-01-11, release date: 2021-01-20, Last modification date: 2021-09-15) |
Primary citation | Zhang, X.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Sexton, P.M.,Belousoff, M.J. Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29:963-, 2021 Cited by PubMed: 33957078DOI: 10.1016/j.str.2021.04.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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