7LCK
PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)
Summary for 7LCK
Entry DOI | 10.2210/pdb7lck/pdb |
Related | 6X1A 7LCI 7LCJ |
EMDB information | 23276 |
Descriptor | Glucagon-like peptide 1 receptor, 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid (3 entities in total) |
Functional Keywords | gpcr, small molecule agonist, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 57304.02 |
Authors | Belousoff, M.J.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Zhang, X.,Sexton, P.M. (deposition date: 2021-01-11, release date: 2021-01-20, Last modification date: 2021-09-15) |
Primary citation | Zhang, X.,Johnson, R.M.,Drulyte, I.,Yu, L.,Kotecha, A.,Danev, R.,Wootten, D.,Sexton, P.M.,Belousoff, M.J. Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29:963-, 2021 Cited by PubMed: 33957078DOI: 10.1016/j.str.2021.04.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.24 Å) |
Structure validation
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