7LCK
PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | R | Glucagon-like peptide 1 receptor | polymer | 491 | 56748.4 | 1 | UniProt (P43220) Pfam (PF02793) Pfam (PF00002) In PDB | Homo sapiens (Human) | GLP-1R |
| 2 | R | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid | non-polymer | 555.6 | 1 | Chemie (UK4) | |||
| 3 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
R: 24 - 463 (UniProt: P43220)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Thr -6 | - | expression tag |
| Ile -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Tyr 0 | - | expression tag |
| Ile 1 | - | expression tag |
| Phe 2 | - | expression tag |
| Cys 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Val 5 | - | expression tag |
| Phe 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Tyr 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Val 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Gln 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Pro 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Phe 260 | Leu 260 | conflict |
| Pro 464 | - | expression tag |
| Ala 465 | - | expression tag |
| Gly 466 | - | expression tag |
| Leu 467 | - | expression tag |
| Glu 468 | - | expression tag |
| Val 469 | - | expression tag |
| Leu 470 | - | expression tag |
| Phe 471 | - | expression tag |
| Gln 472 | - | expression tag |
| Gly 473 | - | expression tag |
| Pro 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
| His 481 | - | expression tag |
| His 482 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56748.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 555.6 | |
| All* | Total formula weight | 57304.0 |
