1N6B
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![BU of 1n6b by Molmil](/molmil-images/mine/1n6b) | Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole | 分子名称: | 4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE, Cytochrome P450 2C5, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Wester, M.R, Johnson, E.F, Marques-Soares, C, Dansette, P.M, Mansuy, D, Stout, C.D. | 登録日 | 2002-11-09 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 A Resolution: Evidence
for Multiple Substrate Binding Modes Biochemistry, 42, 2003
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1L7E
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![BU of 1l7e by Molmil](/molmil-images/mine/1l7e) | Crystal Structure of R. rubrum Transhydrogenase Domain I with Bound NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, nicotinamide nucleotide Transhydrogenase, subunit alpha 1 | 著者 | Prasad, G.S, Wahlberg, M, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | 登録日 | 2002-03-14 | 公開日 | 2002-11-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structures of Transhydrogenase Domain I
with and without Bound NADH Biochemistry, 41, 2002
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1LWL
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![BU of 1lwl by Molmil](/molmil-images/mine/1lwl) | Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide) | 分子名称: | ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Cytochrome P450-cam, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Dunn, A.R, Hays, A.M, Goodin, D.B, Stout, C.D, Chiu, R, Winkler, J.R, Gray, H.B. | 登録日 | 2002-05-31 | 公開日 | 2002-12-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Fluorescent probes for cytochrome P450 structural characterization and inhibitor screening J.AM.CHEM.SOC., 124, 2002
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1NR6
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![BU of 1nr6 by Molmil](/molmil-images/mine/1nr6) | MICROSOMAL CYTOCHROME P450 2C5/3LVDH COMPLEX WITH DICLOFENAC | 分子名称: | 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, CYTOCHROME P450 2C5, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Wester, M.R, Johnson, E.F, Stout, C.D. | 登録日 | 2003-01-23 | 公開日 | 2003-08-12 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Mammalian Cytochrome P450 2C5 Complexed with Diclofenac at 2.1 A Resolution: Evidence for an Induced Fit Model of Substrate Binding Biochemistry, 42, 2003
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1NMU
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![BU of 1nmu by Molmil](/molmil-images/mine/1nmu) | MBP-L30 | 分子名称: | 60S ribosomal protein L30, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding periplasmic protein | 著者 | Chao, J.A, Prasad, G.S, White, S.A, Stout, C.D, Williamson, J.R. | 登録日 | 2003-01-10 | 公開日 | 2003-02-18 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Inherent Protein Structural Flexibility at the RNA-binding Interface of L30e J.Mol.Biol., 326, 2003
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1NYK
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![BU of 1nyk by Molmil](/molmil-images/mine/1nyk) | Crystal Structure of the Rieske protein from Thermus thermophilus | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, MAGNESIUM ION, Rieske iron-sulfur protein | 著者 | Hunsicker-Wang, L.M, Heine, A, Chen, Y, Luna, E.P, Todaro, T, Zhang, Y.M, Williams, P.A, McRee, D.E, Hirst, J, Stout, C.D, Fee, J.A. | 登録日 | 2003-02-12 | 公開日 | 2003-06-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | High resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: Analysis and Comparison Biochemistry, 42, 2003
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1R0Q
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![BU of 1r0q by Molmil](/molmil-images/mine/1r0q) | Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme | 分子名称: | 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 | 著者 | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | 登録日 | 2003-09-22 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
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1QYZ
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![BU of 1qyz by Molmil](/molmil-images/mine/1qyz) | Characterization of the malformed, recombinant cytochrome rC552 | 分子名称: | 2-ACETYL-PROTOPORPHYRIN IX, Cytochrome c-552 | 著者 | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | 登録日 | 2003-09-12 | 公開日 | 2004-09-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
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1R9O
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![BU of 1r9o by Molmil](/molmil-images/mine/1r9o) | Crystal Structure of P4502C9 with Flurbiprofen bound | 分子名称: | Cytochrome P450 2C9, FLURBIPROFEN, GLYCEROL, ... | 著者 | Wester, M.R, Yano, J.K, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F. | 登録日 | 2003-10-30 | 公開日 | 2004-06-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution J.Biol.Chem., 279, 2004
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1RF9
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![BU of 1rf9 by Molmil](/molmil-images/mine/1rf9) | Crystal structure of cytochrome P450-cam with a fluorescent probe D-4-AD (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-butyl-amide) | 分子名称: | 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-BUTYL-AMIDE, Cytochrome P450-cam, ... | 著者 | Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B. | 登録日 | 2003-11-07 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Conformational States of Cytochrome P450cam Revealed by Trapping of synthetic Molecular Wires J.Mol.Biol., 344, 2004
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1RE9
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![BU of 1re9 by Molmil](/molmil-images/mine/1re9) | CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM WITH A FLUORESCENT PROBE D-8-AD (ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE) | 分子名称: | 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Cytochrome P450-cam, ... | 著者 | Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B. | 登録日 | 2003-11-06 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. J.Mol.Biol., 344, 2004
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1PNQ
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![BU of 1pnq by Molmil](/molmil-images/mine/1pnq) | Crystal structure of R. rubrum transhydrogenase domain III bound to NADPH | 分子名称: | NAD(P) transhydrogenase subunit beta, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Sundaresan, V, Yamaguchi, M, Chartron, J, Stout, C.D. | 登録日 | 2003-06-12 | 公開日 | 2003-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational Change in the NADP(H) Binding Domain of Transhydrogenase Defines Four States Biochemistry, 42, 2003
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1PNO
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![BU of 1pno by Molmil](/molmil-images/mine/1pno) | Crystal structure of R. rubrum transhydrogenase domain III bound to NADP | 分子名称: | NAD(P) transhydrogenase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Sundaresan, V, Yamaguchi, M, Chartron, J, Stout, C.D. | 登録日 | 2003-06-12 | 公開日 | 2003-11-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational Change in the NADP(H) Binding Domain of Transhydrogenase Defines Four States Biochemistry, 42, 2003
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1PO5
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![BU of 1po5 by Molmil](/molmil-images/mine/1po5) | Structure of mammalian cytochrome P450 2B4 | 分子名称: | Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Scott, E.E, He, Y.A, Wester, M.R, White, M.A, Chin, C.C, Halpert, J.R, Johnson, E.F, Stout, C.D. | 登録日 | 2003-06-13 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An open conformation of mammalian cytochrome P450 2B4 at 1.6 A resolution Proc.Natl.Acad.Sci.USA, 100, 2003
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1PQ2
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![BU of 1pq2 by Molmil](/molmil-images/mine/1pq2) | Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8 | 分子名称: | Cytochrome P450 2C8, PALMITIC ACID, PHOSPHATE ION, ... | 著者 | Schoch, G.A, Yano, J.K, Wester, M.R, Griffin, K.J, Stout, C.D, Johnson, E.F. | 登録日 | 2003-06-17 | 公開日 | 2004-01-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site J.Biol.Chem., 279, 2004
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3PM0
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![BU of 3pm0 by Molmil](/molmil-images/mine/3pm0) | |
3QM4
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![BU of 3qm4 by Molmil](/molmil-images/mine/3qm4) | Human Cytochrome P450 (CYP) 2D6 - Prinomastat Complex | 分子名称: | Cytochrome P450 2D6, NICKEL (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Wang, A, Stout, C.D, Johnson, E.F. | 登録日 | 2011-02-03 | 公開日 | 2012-02-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound. J.Biol.Chem., 287, 2012
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3QU8
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![BU of 3qu8 by Molmil](/molmil-images/mine/3qu8) | Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. | 分子名称: | 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | 著者 | Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. | 登録日 | 2011-02-23 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
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3QOA
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![BU of 3qoa by Molmil](/molmil-images/mine/3qoa) | Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine. | 分子名称: | 4-benzylpyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | 著者 | Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. | 登録日 | 2011-02-09 | 公開日 | 2011-09-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
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3OGQ
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![BU of 3ogq by Molmil](/molmil-images/mine/3ogq) | Crystal Structure of 6s-98S FIV Protease with Lopinavir bound | 分子名称: | DIMETHYL SULFOXIDE, FIV protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE | 著者 | Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D. | 登録日 | 2010-08-17 | 公開日 | 2011-06-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallogr.,Sect.D, 67, 2011
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3OGP
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![BU of 3ogp by Molmil](/molmil-images/mine/3ogp) | Crystal Structure of 6s-98S FIV Protease with Darunavir bound | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, DIMETHYL SULFOXIDE, FIV Protease | 著者 | Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D. | 登録日 | 2010-08-17 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallogr.,Sect.D, 67, 2011
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3S33
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![BU of 3s33 by Molmil](/molmil-images/mine/3s33) | Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization | 分子名称: | COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | 著者 | Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. | 登録日 | 2011-05-17 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.45 Å) | 主引用文献 | Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
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3S3C
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![BU of 3s3c by Molmil](/molmil-images/mine/3s3c) | Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization | 分子名称: | COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | 著者 | Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. | 登録日 | 2011-05-18 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
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3S38
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![BU of 3s38 by Molmil](/molmil-images/mine/3s38) | Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization | 分子名称: | COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | 著者 | Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. | 登録日 | 2011-05-17 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
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3S8G
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![BU of 3s8g by Molmil](/molmil-images/mine/3s8g) | 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ... | 著者 | Tiefenbrunn, T, Liu, W, Chen, Y, Katritch, V, Stout, C.D, Fee, J.A, Cherezov, V. | 登録日 | 2011-05-27 | 公開日 | 2011-08-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. Plos One, 6, 2011
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