3PM0

Structural Characterization of the Complex between Alpha-Naphthoflavone and Human Cytochrome P450 1B1 (CYP1B1)

Summary for 3PM0

• Entry DOI: 10.2210/pdb3pm0/pdb
• Related: 2HI4
• Descriptor: Cytochrome P450 1B1, PROTOPORPHYRIN IX CONTAINING FE, 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, ... (4 entities in total)
• Functional Keywords: cyp1b1, p450 1b1, p450, monooxygenase, alpha-naphthoflavone, heme, 17beta-estradiol, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein: Q16678
• Total number of polymer chains: 1
• Total formula weight: 57792.73

Authors

Wang, A.,Stout, C.D.,Johnson, E.F. (deposition date: 2010-11-15, release date: 2010-12-08, Last modification date: 2024-02-21)

• Primary citation: Wang, A.,Savas, U.,Stout, C.D.,Johnson, E.F.; Structural Characterization of the Complex between {alpha}-Naphthoflavone and Human Cytochrome P450 1B1.; J.Biol.Chem., 286:5736-5743, 2011; PubMed: 21147782; DOI: 10.1074/jbc.M110.204420

Experimental method

X-RAY DIFFRACTION (2.7 Å)