1LWL

Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide)

Summary for 1LWL

Related	1K2O 1QMQ
Descriptor	Cytochrome P450-cam, PROTOPORPHYRIN IX CONTAINING FE, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, ... (4 entities in total)
Functional Keywords	monooxygenase, electron transfer, energy transfer, substrate-binding, dansyl, adamantane, adamantane-1-carboxylic acid [4-(5-dimethylamino-naphthalene-1-sulfonylamino)-octyl]-amide, channel, oxidoreductase
Biological source	Pseudomonas putida
Cellular location	Cytoplasm (By similarity): P00183
Total number of polymer chains	1
Total formula weight	48117.62
Authors	Dunn, A.R.,Hays, A.M.,Goodin, D.B.,Stout, C.D.,Chiu, R.,Winkler, J.R.,Gray, H.B. (deposition date: 2002-05-31, release date: 2002-12-18, Last modification date: 2011-07-13)
Primary citation	Chiu, R.,Dunn, A.R.,Goodin, D.B.,Gray, H.B.,Hays, A.M.,Stout, C.D.,Winkler, J.R. Fluorescent probes for cytochrome P450 structural characterization and inhibitor screening J.AM.CHEM.SOC., 124:10254-10255, 2002 PubMed: 12197708 DOI: 110.1021/ja0271678 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation