3QM4
Human Cytochrome P450 (CYP) 2D6 - Prinomastat Complex
Summary for 3QM4
Entry DOI | 10.2210/pdb3qm4/pdb |
Related | 2f9q |
Descriptor | Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, Prinomastat, ... (5 entities in total) |
Functional Keywords | cyp2d6, p450 2d6, p450, monooxygenase, prinomastat, heme, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P10635 |
Total number of polymer chains | 2 |
Total formula weight | 109599.81 |
Authors | Wang, A.,Stout, C.D.,Johnson, E.F. (deposition date: 2011-02-03, release date: 2012-02-15, Last modification date: 2023-09-13) |
Primary citation | Wang, A.,Savas, U.,Hsu, M.H.,Stout, C.D.,Johnson, E.F. Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound. J.Biol.Chem., 287:10834-10843, 2012 Cited by PubMed: 22308038DOI: 10.1074/jbc.M111.307918 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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