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4F2J
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BU of 4f2j by Molmil
Crystal structure of ZNF217 bound to DNA, P6522 crystal form
分子名称: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3', ZINC ION, Zinc finger protein 217
著者Vandevenne, M.S, Jacques, D.A, Guss, J.M, Mackay, J.P.
登録日2012-05-08
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217
J.Biol.Chem., 288, 2013
4X5S
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BU of 4x5s by Molmil
The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase (Carbonate dehydratase), ...
著者De Simone, G, Alterio, V, Di Fiore, A.
登録日2014-12-05
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense.
Bioorg.Med.Chem.Lett., 25, 2015
6OKO
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BU of 6oko by Molmil
Crystal structure of mRIPK3 complexed with N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
分子名称: 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3
著者Pokross, M.E.
登録日2019-04-14
公開日2019-07-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Acs Med.Chem.Lett., 11, 2020
5KW1
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BU of 5kw1 by Molmil
Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue
分子名称: CHLORIDE ION, DNA/RNA (30-MER), Poly(U)-binding-splicing factor PUF60
著者Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
登録日2016-07-15
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KVY
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BU of 5kvy by Molmil
CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
分子名称: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60
著者Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T.
登録日2016-07-15
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
3IJJ
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BU of 3ijj by Molmil
Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)
分子名称: (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ...
著者Crichlow, G.V, Cho, Y, Lolis, E.J.
登録日2009-08-04
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IJG
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BU of 3ijg by Molmil
Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013
分子名称: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor
著者Crichlow, G.V, Cho, Y, Lolis, E.J.
登録日2009-08-04
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3P90
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BU of 3p90 by Molmil
Crystal Structure Analysis of H207F Mutant of Human CLIC1
分子名称: Chloride intracellular channel protein 1
著者Cross, M.O, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Dirr, H.W.
登録日2010-10-15
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1.
Biochemistry, 51, 2012
5LLQ
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BU of 5llq by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119F variant
分子名称: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2016-07-28
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.
Biochim.Biophys.Acta, 1861, 2016
1GOW
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BU of 1gow by Molmil
BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
分子名称: BETA-GLYCOSIDASE
著者Pearl, L.H, Aguilar, C.F, Sanderson, I.
登録日1996-09-19
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability.
J.Mol.Biol., 271, 1997
4ZYE
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BU of 4zye by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase
分子名称: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase, NITRATE ION
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
5LBH
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BU of 5lbh by Molmil
Crystal structure of Helicobacter cinaedi CAIP
分子名称: CAIP, FE (III) ION
著者Zanotti, G, Valesse, F, Codolo, G, De Bernard, M.
登録日2016-06-16
公開日2017-04-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells.
Sci Rep, 7, 2017
4ZYG
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BU of 4zyg by Molmil
Crystal structure of methylated Sulfolobus solfataricus O6-methylguanine methyltransferase
分子名称: Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYH
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BU of 4zyh by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant
分子名称: Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4YF5
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BU of 4yf5 by Molmil
Crystal structure of Rv1284 in the presence of polycarpine at acidic pH
分子名称: Beta-carbonic anhydrase 1, CHLORIDE ION, ZINC ION
著者Hofmann, A.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4YF6
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BU of 4yf6 by Molmil
Crystal structure of oxidised Rv1284
分子名称: Beta-carbonic anhydrase 1, CHLORIDE ION, MAGNESIUM ION, ...
著者Hofmann, A.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4YF4
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BU of 4yf4 by Molmil
Crystal structure of Rv1284 in the presence of polycarpine at mildly acidic pH
分子名称: Beta-carbonic anhydrase 1, CHLORIDE ION, MAGNESIUM ION, ...
著者Hofmann, A.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284.
Febs J., 282, 2015
4ZYD
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BU of 4zyd by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
分子名称: DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase
著者Miggiano, R, Rossi, F, Rizzi, M.
登録日2015-05-21
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
5KC6
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BU of 5kc6 by Molmil
Crystal structure of Cbln1 (Val55-Gly58 deletion mutant)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1
著者Elegheert, J, Clay, J.E, Aricescu, A.R.
登録日2016-06-05
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural basis for integration of GluD receptors within synaptic organizer complexes.
Science, 353, 2016
5H0U
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BU of 5h0u by Molmil
Crystal structure of the catalytic domain of membrane type 1 matrix metalloproteinase
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Ogata, H, Decaneto, E, Lubitz, W.
登録日2016-10-07
公開日2017-10-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.239 Å)
主引用文献Solvent water interactions within the active site of the membrane type I matrix metalloproteinase.
Phys Chem Chem Phys, 19, 2017
7P4G
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BU of 7p4g by Molmil
Rabbit Muscle L-lactate dehydrogenase in complex with citrate
分子名称: CITRIC ACID, L-lactate dehydrogenase A chain
著者Iacovino, L.G, Binda, C, Hochkoeppler, A.
登録日2021-07-11
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme.
Biochimie, 199, 2022
1NSW
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BU of 1nsw by Molmil
The Crystal Structure of the K18G Mutant of the thioredoxin from Alicyclobacillus acidocaldarius
分子名称: THIOREDOXIN
著者Bartolucci, S, De Simone, G, Galdiero, S, Improta, R, Menchise, V, Pedone, C, Pedone, E, Saviano, M.
登録日2003-01-28
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
J.Bacteriol., 185, 2003
1NW2
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BU of 1nw2 by Molmil
The crystal structure of the mutant R82E of Thioredoxin from Alicyclobacillus acidocaldarius
分子名称: ACETATE ION, CACODYLATE ION, THIOREDOXIN, ...
著者Bartolucci, S, De Simone, G, Galdiero, S, Improta, R, Menchise, V, Pedone, C, Pedone, E, Saviano, M.
登録日2003-02-05
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius
J.Bacteriol., 185, 2003
4ALO
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BU of 4alo by Molmil
STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ...
著者Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M.
登録日2012-03-05
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus.
Acta Crystallogr.,Sect.F, 68, 2012
3LG8
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BU of 3lg8 by Molmil
Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase
分子名称: A-type ATP synthase subunit E
著者Balakrishna, A.M, Manimekalai, M.S.S, Hunke, C, Gayen, S, Jeyakanthan, J, Gruber, G.
登録日2010-01-19
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering
J.Bioenerg.Biomembr., 42, 2010

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