8A1Q
| HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor STP0404 (Pirmitegravir) | 分子名称: | (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, 1,2-ETHANEDIOL, Integrase, ... | 著者 | Singer, M.R, Pye, V.E, Cook, N.J, Cherepanov, P. | 登録日 | 2022-06-01 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. Mbio, 14, 2023
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7F1W
| X-ray crystal structure of visual arrestin complexed with inositol hexaphosphate | 分子名称: | INOSITOL HEXAKISPHOSPHATE, S-arrestin | 著者 | Kang, M, Jang, K, Eger, B.T, Ernst, O.P, Choe, H.W, Kim, Y.J. | 登録日 | 2021-06-10 | 公開日 | 2021-10-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.097 Å) | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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7F1X
| X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate | 分子名称: | 1,2-ETHANEDIOL, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PENTANEDIAL, ... | 著者 | Jang, K, Kang, M, Eger, B.T, Choe, H.W, Ernst, O.P, Kim, Y.J. | 登録日 | 2021-06-10 | 公開日 | 2021-10-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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2BZW
| The crystal structure of BCL-XL in complex with full-length BAD | 分子名称: | APOPTOSIS REGULATOR BCL-X, BCL2-ANTAGONIST OF CELL DEATH | 著者 | Lee, K.-H, Han, W.-D, Kim, K.-J, Oh, B.-H. | 登録日 | 2005-08-24 | 公開日 | 2007-02-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68. Plos Pathog., 4, 2008
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7MSJ
| The crystal structure of mouse HVEM | 分子名称: | SULFATE ION, Tumor necrosis factor receptor superfamily member 14 | 著者 | Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C. | 登録日 | 2021-05-11 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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7MSG
| The crystal structure of LIGHT in complex with HVEM and CD160 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, ... | 著者 | Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C. | 登録日 | 2021-05-11 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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2JDJ
| crystal structure of HapK from Hahella chejuensis | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, REDY-LIKE PROTEIN, ... | 著者 | Kang, B.S, Cho, H.J, Kim, K.J. | 登録日 | 2007-01-10 | 公開日 | 2007-09-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insight of the Role of the Hahella Chejuensis Hapk Protein in Prodigiosin Biosynthesis. Proteins, 70, 2008
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8I4P
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8IEC
| Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | 著者 | Shin, J, Park, J, Cho, Y. | 登録日 | 2023-02-15 | 公開日 | 2024-02-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IED
| Cryo-EM structure of GPR156-miniGo-scFv16 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | 著者 | Shin, J, Park, J, Cho, Y. | 登録日 | 2023-02-15 | 公開日 | 2024-02-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IEI
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6KIE
| Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form | 分子名称: | 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... | 著者 | Kim, S, Son, J, Kim, S, Hwang, K.Y. | 登録日 | 2019-07-18 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
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8IEB
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8IEP
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8IEQ
| Cryo-EM structure of G-protein free GPR156 | 分子名称: | Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate | 著者 | Shin, J, Park, J, Cho, Y. | 登録日 | 2023-02-15 | 公開日 | 2024-02-14 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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6KID
| Crystal structure of human leucyl-tRNA synthetase, ATP-bound form | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, LEUCINE, Leucine--tRNA ligase, ... | 著者 | Kim, S, Son, J, Kim, S, Hwang, K.Y. | 登録日 | 2019-07-18 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation. Cell Rep, 35, 2021
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4XB2
| Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH | 分子名称: | 319aa long hypothetical homoserine dehydrogenase, L-HOMOSERINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. | 登録日 | 2014-12-16 | 公開日 | 2015-07-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases. Sci Rep, 5, 2015
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4XB1
| Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. | 登録日 | 2014-12-16 | 公開日 | 2015-07-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases. Sci Rep, 5, 2015
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2RVC
| Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase | 分子名称: | Interferon-inducible and double-stranded-dependent eIF-2kinase | 著者 | Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J. | 登録日 | 2015-07-08 | 公開日 | 2016-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition. Nucleic Acids Res., 44, 2016
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7KDT
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4RSU
| Crystal structure of the light and hvem complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-11-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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4ML7
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4MIR
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8K55
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8K57
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