2BZW
The crystal structure of BCL-XL in complex with full-length BAD
Summary for 2BZW
Entry DOI | 10.2210/pdb2bzw/pdb |
Related | 1PQ0 1PQ1 |
Descriptor | APOPTOSIS REGULATOR BCL-X, BCL2-ANTAGONIST OF CELL DEATH (3 entities in total) |
Functional Keywords | transcription, apoptosis, phosphorylation, transcription complex, mitochondrion, transmembrane |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Cellular location | Mitochondrion membrane ; Single-pass membrane protein . Isoform Bcl-X(L): Mitochondrion inner membrane. Isoform Bcl-X(delta-TM): Cytoplasm: Q64373 Mitochondrion outer membrane: Q61337 |
Total number of polymer chains | 2 |
Total formula weight | 26950.58 |
Authors | Lee, K.-H.,Han, W.-D.,Kim, K.-J.,Oh, B.-H. (deposition date: 2005-08-24, release date: 2007-02-13, Last modification date: 2024-05-08) |
Primary citation | Ku, B.,Woo, J.,Liang, C.,Lee, K.,Hong, H.,Xiaofeni, E.,Kim, K.,Jung, J.U.,Oh, B. Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68. Plos Pathog., 4:E25-, 2008 Cited by PubMed: 18248095DOI: 10.1371/JOURNAL.PPAT.0040025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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