7Y5O
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![BU of 7y5o by Molmil](/molmil-images/mine/7y5o) | Crystal structure of human CAF-1 core complex in spacegroup P21 | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5U
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![BU of 7y5u by Molmil](/molmil-images/mine/7y5u) | Cryo-EM structure of the monomeric human CAF1LC-H3-H4 complex | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5W
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![BU of 7y5w by Molmil](/molmil-images/mine/7y5w) | Cryo-EM structure of the left-handed Di-tetrasome | 分子名称: | Histone H3.1, Histone H4, Widom 601 DNA (147-MER) | 著者 | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y60
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![BU of 7y60 by Molmil](/molmil-images/mine/7y60) | Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M. | 登録日 | 2022-06-18 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7Y5L
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![BU of 7y5l by Molmil](/molmil-images/mine/7y5l) | Crystal structure of human CAF-1 core complex in spacegroup C2 | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ... | 著者 | Liu, C.P, Wang, M.Z, Xu, R.M. | 登録日 | 2022-06-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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7XNK
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![BU of 7xnk by Molmil](/molmil-images/mine/7xnk) | human KCNQ1-CaM in complex with ML277 | 分子名称: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-29 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XNL
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![BU of 7xnl by Molmil](/molmil-images/mine/7xnl) | human KCNQ1-CaM-ML277-PIP2 complex in state A | 分子名称: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-29 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XNI
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![BU of 7xni by Molmil](/molmil-images/mine/7xni) | human KCNQ1-CaM in apo state | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 1 | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-28 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XNN
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![BU of 7xnn by Molmil](/molmil-images/mine/7xnn) | human KCNQ1-CaM-ML277-PIP2 complex in state B | 分子名称: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-29 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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6MIE
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![BU of 6mie by Molmil](/molmil-images/mine/6mie) | Solution NMR structure of the KCNQ1 voltage-sensing domain | 分子名称: | Potassium voltage-gated channel subfamily KQT member 1 | 著者 | Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R. | 登録日 | 2018-09-19 | 公開日 | 2020-03-04 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, 2020
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6IUV
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![BU of 6iuv by Molmil](/molmil-images/mine/6iuv) | Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3C11 Heavy Chain, 3C11 Light Chain, ... | 著者 | Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. | 登録日 | 2018-11-30 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.332 Å) | 主引用文献 | Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1. J. Biol. Chem., 294, 2019
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6IEW
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![BU of 6iew by Molmil](/molmil-images/mine/6iew) | |
6IHJ
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4Y76
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![BU of 4y76 by Molmil](/molmil-images/mine/4y76) | Factor Xa complex with GTC000401 | 分子名称: | CALCIUM ION, Coagulation factor X, N~2~-[(6-chloronaphthalen-2-yl)sulfonyl]-N~2~-{(3S)-1-[(2S)-1-(4-methyl-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}glycinamide | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | 登録日 | 2015-02-13 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides. J. Med. Chem., 50, 2007
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4Y79
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![BU of 4y79 by Molmil](/molmil-images/mine/4y79) | Factor Xa complex with GTC000406 | 分子名称: | (E)-2-(4-chlorophenyl)-N-{(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}ethenesulfonamide, CALCIUM ION, Coagulation factor X, ... | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | 登録日 | 2015-02-13 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides. J. Med. Chem., 50, 2007
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2I50
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![BU of 2i50 by Molmil](/molmil-images/mine/2i50) | Solution Structure of Ubp-M Znf-UBP domain | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 16, ZINC ION | 著者 | Pai, M.-T. | 登録日 | 2006-08-23 | 公開日 | 2007-08-07 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin. J.Mol.Biol., 370, 2007
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4IHF
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![BU of 4ihf by Molmil](/molmil-images/mine/4ihf) | Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | Acyl carrier protein, CHLORIDE ION, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxytetradecanethioate, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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4IHH
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![BU of 4ihh by Molmil](/molmil-images/mine/4ihh) | Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.132 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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4IHG
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![BU of 4ihg by Molmil](/molmil-images/mine/4ihg) | Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | 3-HYDROXY-TETRADECANOIC ACID, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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7OX9
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![BU of 7ox9 by Molmil](/molmil-images/mine/7ox9) | Target-bound SpCas9 complex with AAVS1 all-RNA guide | 分子名称: | AAVS1 non-target DNA strand, AAVS1 target DNA strand, CRISPR-associated endonuclease Cas9/Csn1, ... | 著者 | Pacesa, M, Donohoue, P, May, A.P, Jinek, M, Cameron, P. | 登録日 | 2021-06-22 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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4Y7B
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![BU of 4y7b by Molmil](/molmil-images/mine/4y7b) | Factor Xa complex with GTC000441 | 分子名称: | 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopy rrolidin-3-yl}naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | 登録日 | 2015-02-13 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Factor Xa complex with GTC000441 to be published
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4Y71
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![BU of 4y71 by Molmil](/molmil-images/mine/4y71) | Factor Xa complex with GTC000398 | 分子名称: | 6-chloro-N-{(3S)-1-[(2S)-1-(4-methyl-5-oxo-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulf onamide, CALCIUM ION, Coagulation factor X | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | 登録日 | 2015-02-13 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Factor Xa complex with GTC000398 To be Published
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4Y7A
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![BU of 4y7a by Molmil](/molmil-images/mine/4y7a) | Factor Xa complex with GTC000422 | 分子名称: | CALCIUM ION, Coagulation factor X, MAGNESIUM ION, ... | 著者 | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | 登録日 | 2015-02-13 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Factor Xa complex with GTC000422 to be published
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7NAB
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![BU of 7nab by Molmil](/molmil-images/mine/7nab) | Crystal structure of human neutralizing mAb CV3-25 binding to SARS-CoV-2 S MPER peptide 1140-1165 | 分子名称: | CITRIC ACID, CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, ... | 著者 | Chen, Y, Tolbert, W.D, Pazgier, M. | 登録日 | 2021-06-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern. Cell Rep, 38, 2022
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8VYE
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![BU of 8vye by Molmil](/molmil-images/mine/8vye) | SARS-CoV-2 S (C.37 Lambda variant) plus S309, S2L20, and S2X303 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, S2L20 Light Chain, ... | 著者 | McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2024-02-08 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
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