7XNK

human KCNQ1-CaM in complex with ML277

Summary for 7XNK

• Entry DOI: 10.2210/pdb7xnk/pdb
• EMDB information: 33317
• Descriptor: Potassium voltage-gated channel subfamily KQT member 1, Calmodulin-3, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: potassium voltage-gated channel, ml277, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 386453.73

Authors

Ma, D.,Guo, J. (deposition date: 2022-04-29, release date: 2022-12-14, Last modification date: 2023-02-22)

• Primary citation: Ma, D.,Zhong, L.,Yan, Z.,Yao, J.,Zhang, Y.,Ye, F.,Huang, Y.,Lai, D.,Yang, W.,Hou, P.,Guo, J.; Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.; Proc.Natl.Acad.Sci.USA, 119:e2207067119-e2207067119, 2022; PubMed: 36763058; DOI: 10.1073/pnas.2207067119

Experimental method

ELECTRON MICROSCOPY (2.6 Å)