3TC6
 
 | | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. | | 分子名称: | DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | | 著者 | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-08-08 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
|
|
3TC7
 | | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62. | | 分子名称: | ACETIC ACID, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | | 著者 | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-08-08 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
|
|
5EC0
 | | Crystal Structure of Actin-like protein Alp7A | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alp7A, GLYCEROL, ... | | 著者 | Petek, N.A, Kraemer, J.A, Mullins, R.D, Agard, D.A, DiMaio, F, Baker, D. | | 登録日 | 2015-10-20 | | 公開日 | 2016-11-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and function of Alp7A reveal both conserved and unique features of plasmid segregation.
To Be Published
|
|
5EIL
 | | Computational design of a high-affinity metalloprotein homotrimer containing a metal chelating non-canonical amino acid | | 分子名称: | FE (III) ION, TRI-05 | | 著者 | Sankaran, B, Zwart, P.H, Mills, J.H, Pereira, J.H, Baker, D. | | 登録日 | 2015-10-30 | | 公開日 | 2016-11-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
|
|
3U13
 | | Crystal Structure of de Novo design of cystein esterase ECH13 at the resolution 1.6A, Northeast Structural Genomics Consortium Target OR51 | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Kohan, E, Richter, F, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-09-29 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
|
|
3U1O
 | | THREE DIMENSIONAL STRUCTURE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH19, Northeast Structural Genomics Consortium Target OR49 | | 分子名称: | De Novo design cysteine esterase ECH19, SODIUM ION, SULFATE ION | | 著者 | Kuzin, A, Su, M, Lew, S, Forouhar, F, Seetharaman, J, Daya, P, Xiao, R, Ciccosanti, C, Richter, F, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-09-30 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | | 主引用文献 | Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
|
|
3J03
 | | Lidless Mm-cpn in the closed state with ATP/AlFx | | 分子名称: | Lidless Mm-cpn | | 著者 | Zhang, J, Ma, B, DiMaio, F, Douglas, N.R, Joachimiak, L, Baker, D, Frydman, J, Levitt, M, Chiu, W. | | 登録日 | 2011-02-10 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
|
|
6UG2
 | | C2 symmetric peptide design number 1, Zappy, crystal form 2 | | 分子名称: | C2-1, Zappy, crystal form 2, ... | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-25 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UFA
 | | S4 symmetric peptide design number 1, Tim zinc-bound form | | 分子名称: | S4-1, Tim, Zinc-bound form, ... | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-24 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (0.77 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UF4
 | | S2 symmetric peptide design number 4 crystal form 2, Pugsley | | 分子名称: | S2-4, Pusgley crystal form 2 | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-23 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UF9
 | | S4 symmetric peptide design number 1, Tim apo form | | 分子名称: | S4-1, Tim apo-form, SULFATE ION | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-24 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UG6
 | | C3 symmetric peptide design number 1, Sporty, crystal form 2 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, C3-1, ... | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-25 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UDW
 | | S2 symmetric peptide design number 3 crystal form 2, Lurch | | 分子名称: | S2-3, Lurch crystal form 2 | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-19 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UGB
 | | C3 symmetric peptide design number 2, Baby Basil | | 分子名称: | C3 symmetric peptide design number 2, Baby Basil, CHLORIDE ION, ... | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UF7
 | | S2 symmetric peptide design number 5, Uncle Fester | | 分子名称: | S2-5, Uncle Fester | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-23 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UF8
 | | S2 symmetric peptide design number 6, London Bridge | | 分子名称: | S2-6, London Bridge | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-23 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UFU
 | | C2 symmetric peptide design number 1, Zappy, crystal form 1 | | 分子名称: | C2-1, Zappy, crystal form 1 | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-25 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UG3
 | | C3 symmetric peptide design number 1, Sporty, crystal form 1 | | 分子名称: | C3-1, Sporty, crystal form 1, ... | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-25 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UGC
 | | C3 symmetric peptide design number 3 | | 分子名称: | C3-3 cyclic peptide design, CADMIUM ION, SODIUM ION | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UDR
 | | S2 symmetric peptide design number 3 crystal form 1, Lurch | | 分子名称: | S2-3, Lurch crystal form 1 | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-19 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UD9
 | | S2 symmetric peptide design number 2, Morticia | | 分子名称: | S2-2, Morticia | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-19 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UCX
 | | S2 symmetric peptide design number 1, Wednesday | | 分子名称: | S2-1, Wednesday, trifluoroacetic acid | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-18 | | 公開日 | 2020-09-23 | | 最終更新日 | 2021-07-28 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6UDZ
 | | S2 symmetric peptide design number 4 crystal form 1, Pugsley | | 分子名称: | S2-4, Pusgley crystal form 1, trifluoroacetic acid | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-20 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-02 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
|
|
6V67
 | | Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2 | | 分子名称: | PD-1 Binding Miniprotein GR918.2 | | 著者 | Bick, M.J, Bryan, C.M, Baker, D, Dimaio, F, Kang, A. | | 登録日 | 2019-12-04 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Computational design of a synthetic PD-1 agonist.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
4A2R
 | | Structure of the engineered retro-aldolase RA95.5-5 | | 分子名称: | 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE | | 著者 | Giger, L, Caner, S, Kast, P, Baker, D, Ban, N, Hilvert, D. | | 登録日 | 2011-09-28 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | Evolution of a designed retro-aldolase leads to complete active site remodeling.
Nat.Chem.Biol., 9, 2013
|
|
