4ESS
Crystal Structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium (NESG) Target OR187
Summary for 4ESS
Entry DOI | 10.2210/pdb4ess/pdb |
Related | 3V45 |
Descriptor | OR187 (2 entities in total) |
Functional Keywords | structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium (nesg) target or187, osh55 mutant e6d/l159r, serine hydrolase, de novo protein, hydrolase |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 17705.25 |
Authors | Kuzin, A.,Su, M.,Seetharaman, J.,Kornhaber, K.,Kornhaber, G.,Rajagopalan, S.,Baker, D.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2012-04-23, release date: 2012-06-13, Last modification date: 2023-09-13) |
Primary citation | Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10:386-391, 2014 Cited by PubMed: 24705591DOI: 10.1038/nchembio.1498 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9971 Å) |
Structure validation
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