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4Y6K
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BU of 4y6k by Molmil
Complex structure of presenilin homologue PSH bound to an inhibitor
分子名称: N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide, Uncharacterized protein PSH
著者Dang, S, Wu, S, Wang, J, Shi, Y.
登録日2015-02-13
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.855 Å)
主引用文献Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
Proc.Natl.Acad.Sci.USA, 112, 2015
5UN8
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BU of 5un8 by Molmil
Crystal Structure of human O-GlcNAcase in complex with glycopeptide p53
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P53 peptide, Protein O-GlcNAcase
著者Li, B, Jiang, J.
登録日2017-01-30
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5UN9
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BU of 5un9 by Molmil
The crystal structure of human O-GlcNAcase in complex with Thiamet-G
分子名称: (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, Protein O-GlcNAcase
著者Li, B, Jiang, J.
登録日2017-01-30
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
分子名称: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
著者Wang, C, Zhang, P, Dong, J.
登録日2016-03-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5TKE
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BU of 5tke by Molmil
Crystal Structure of Eukaryotic Hydrolase
分子名称: O-GlcNAcase: chimera construct
著者Li, B, Jiang, J.
登録日2016-10-06
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.481 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
3KPH
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BU of 3kph by Molmil
Crystal structure of Mycoplasma arthritidis-derived mitogen
分子名称: PHOSPHATE ION, Superantigen
著者Liu, L.H, Li, H.M.
登録日2009-11-16
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer.
J.Mol.Biol., 399, 2010
7LIR
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BU of 7lir by Molmil
Structure of the invertebrate ALK GRD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ...
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-01-27
公開日2021-11-24
最終更新日2021-12-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LS0
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BU of 7ls0 by Molmil
Structure of the Human ALK GRD bound to AUG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-02-17
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LRZ
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BU of 7lrz by Molmil
Structure of the Human ALK GRD
分子名称: ALK tyrosine kinase receptor
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-02-17
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
分子名称: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
著者Manne, K, Nicely, N.I, Acharya, P.
登録日2020-07-13
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
4Z62
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BU of 4z62 by Molmil
The plant peptide hormone free receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Phytosulfokine receptor 1
著者Chai, J, Wang, J, Han, Z.
登録日2015-04-03
公開日2016-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z5W
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BU of 4z5w by Molmil
The plant peptide hormone receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phytosulfokine, ...
著者Chai, J, Wang, J, Han, Z.
登録日2015-04-03
公開日2016-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z61
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BU of 4z61 by Molmil
The plant peptide hormone receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-ILE-PTR-THR-GLN, Phytosulfokine receptor 1, ...
著者Chai, J, Wang, J.
登録日2015-04-03
公開日2016-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z64
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BU of 4z64 by Molmil
the plant peptide hormone receptor complex in arabidopsis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phytosulfokine, ...
著者Chai, J, Wang, J, Han, Z.
登録日2015-04-03
公開日2016-03-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.659 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
7MSQ
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BU of 7msq by Molmil
Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)
分子名称: AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, CHLORIDE ION, ...
著者Langley, D.B, Christ, D.
登録日2021-05-12
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Immunity, 54, 2021
4Z63
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BU of 4z63 by Molmil
The plant peptide hormone receptor in arabidopsis
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Phytosulfokine, Phytosulfokine receptor 1
著者Chai, J, Wang, J, Han, Z.
登録日2015-04-03
公開日2016-03-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.514 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
7E3O
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BU of 7e3o by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody nCoV617
分子名称: Spike protein S1, nCoV617 Heigh Chain, nCoV617 Light Chain
著者Chen, S.D, Yang, M.
登録日2021-02-09
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Basis of a Human Neutralizing Antibody Specific to the SARS-CoV-2 Spike Protein Receptor-Binding Domain.
Microbiol Spectr, 9, 2021
5XTZ
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BU of 5xtz by Molmil
Crystal structure of GAS41 YEATS bound to H3K27ac peptide
分子名称: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4
著者Li, H.T, Zhao, D.
登録日2017-06-21
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
6MIN
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BU of 6min by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIM
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BU of 6mim by Molmil
Crystal structure of AF9 YEATS domain Y78W mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Protein AF-9
著者Vann, K.R, Klein, B.J, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.525 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIO
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BU of 6mio by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr
分子名称: Histone H3K9pr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIQ
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BU of 6miq by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu
分子名称: Histone H3K9bu, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIP
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BU of 6mip by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant
分子名称: DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIL
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BU of 6mil by Molmil
Crystal structure of AF9 YEATS domain in complex with histone H3K9bu
分子名称: DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ...
著者Vann, K.R, Klein, B.J, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
4R0X
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BU of 4r0x by Molmil
Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5
著者LeMaster, D.M, Mustafi, S.M, Brecher, M, Zhang, J, Heroux, A, Li, H.M, Hernandez, G.
登録日2014-08-02
公開日2015-05-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
J.Biol.Chem., 290, 2015

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