6UIG
 
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2YEL
 | | Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor GW841819X | | 分子名称: | 1,2-ETHANEDIOL, BENZYL [(4R)-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPIN-4-YL]CARBAMATE, HUMAN BRD4 | | 著者 | Chung, C.W. | | 登録日 | 2011-03-25 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
J.Med.Chem., 54, 2011
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2YEM
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2YDW
 | | Crystal Structure of the First Bromodomain of Human Brd2 with the inhibitor GW841819X | | 分子名称: | BENZYL [(4R)-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPIN-4-YL]CARBAMATE, BROMODOMAIN-CONTAINING PROTEIN 2, SULFATE ION | | 著者 | Chung, C, Delves, C, Woodward, R, Mirguet, O, Nicodeme, E. | | 登録日 | 2011-03-24 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
J.Med.Chem., 54, 2011
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3C7N
 | | Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ... | | 著者 | Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R. | | 登録日 | 2008-02-07 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.115 Å) | | 主引用文献 | Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
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7PBC
 | | Crystal structure of engineered TCR (796) complexed to HLA-A*02:01 presenting MAGE-A10 9-mer peptide | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | 著者 | Simister, P.C, Border, E.C, Vieira, J.F, Pumphrey, N.J. | | 登録日 | 2021-08-02 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
J Immunother Cancer, 10, 2022
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2Z5G
 | | Crystal structure of T1 lipase F16L mutant | | 分子名称: | CALCIUM ION, CHLORIDE ION, Thermostable lipase, ... | | 著者 | Matsumura, H, Yamamoto, T, Inoue, T, Kai, Y. | | 登録日 | 2007-07-08 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase
Proteins, 70, 2007
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3CQX
 | | Chaperone Complex | | 分子名称: | BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ... | | 著者 | Xu, Z, Nix, J.C, Misra, S. | | 登録日 | 2008-04-03 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2
Nat.Struct.Mol.Biol., 15, 2008
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3D0T
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2MGU
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2M3S
 | | Calmodulin, i85l, f92e, h107i, l112r, a128t, m144r mutant | | 分子名称: | CALCIUM ION, Calmodulin | | 著者 | Moroz, Y.S, Wu, Y, Cheng, H, Roder, H, Korendovych, I.V. | | 登録日 | 2013-01-25 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction.
Angew.Chem.Int.Ed.Engl., 52, 2013
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1FQE
 | | CRYSTAL STRUCTURES OF MUTANT (K206A) THAT ABOLISH THE DILYSINE INTERACTION IN THE N-LOBE OF HUMAN TRANSFERRIN | | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | 著者 | Nurizzo, D, Baker, H.M, Baker, E.N. | | 登録日 | 2000-09-04 | | 公開日 | 2001-05-16 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.
Biochemistry, 40, 2001
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1FQF
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2N1T
 | | Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution | | 分子名称: | Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ... | | 著者 | Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J. | | 登録日 | 2015-04-21 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.
Nat.Struct.Mol.Biol., 22, 2015
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2N55
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2P54
 | | a crystal structure of PPAR alpha bound with SRC1 peptide and GW735 | | 分子名称: | 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor alpha | | 著者 | Xu, R.X, Xu, H.E, Sierra, M.L, Montana, V.G, Lambert, M.H, Pianetti, P.M. | | 登録日 | 2007-03-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPAR Agonists. 1.Discovery of a Novel Series of Potent HDLc Raising Agents.
J.Med.Chem., 50, 2007
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2O68
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2O6A
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2O69
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1GUI
 | | CBM4 structure and function | | 分子名称: | CALCIUM ION, GLYCEROL, LAMINARINASE 16A, ... | | 著者 | Nurizzo, D, Notenboom, V, Davies, G.J. | | 登録日 | 2002-01-27 | | 公開日 | 2002-09-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Differential Oligosaccharide Recognition by Evolutionarily-Related Beta-1,4 and Beta-1,3 Glucan-Binding Modules
J.Mol.Biol., 319, 2002
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2OZN
 | | The Cohesin-Dockerin Complex of NagJ and NagH from Clostridium perfringens | | 分子名称: | CALCIUM ION, CHLORIDE ION, Hyalurononglucosaminidase, ... | | 著者 | Adams, J.J, Boraston, A, Smith, S.P. | | 登録日 | 2007-02-26 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of Clostridium perfringens toxin complex formation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2P55
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1HC9
 | | alpha-bungarotoxin complexed with high affinity peptide | | 分子名称: | ALPHA-BUNGAROTOXIN ISOFORM A31, ALPHA-BUNGAROTOXIN ISOFORM V31, IODIDE ION, ... | | 著者 | Harel, M, Kasher, R, Sussman, J.L. | | 登録日 | 2001-05-02 | | 公開日 | 2001-11-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Binding Site of Acetylcholine Receptor as Visualized in the X-Ray Structure of a Complex between Alpha-Bungarotoxin and a Mimotope Peptide.
Neuron, 32, 2001
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1GU3
 | | CBM4 structure and function | | 分子名称: | ENDOGLUCANASE C, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Nurizzo, D, Notenboom, V, Davies, G.J. | | 登録日 | 2002-01-22 | | 公開日 | 2002-09-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Differential Oligosaccharide Recognition by Evolutionarily-Related Beta-1,4 and Beta-1,3 Glucan-Binding Modules
J.Mol.Biol., 319, 2002
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2PBK
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