6WGI
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![BU of 6wgi by Molmil](/molmil-images/mine/6wgi) | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WIV
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![BU of 6wiv by Molmil](/molmil-images/mine/6wiv) | Structure of human GABA(B) receptor in an inactive state | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Park, J, Fu, Z, Frangaj, A, Liu, J, Mosyak, L, Shen, T, Slavkovich, V.N, Ray, K.M, Taura, J, Cao, B, Geng, Y, Zuo, H, Kou, Y, Grassucci, R, Chen, S, Liu, Z, Lin, X, Williams, J.P, Rice, W.J, Eng, E.T, Huang, R.K, Soni, R.K, Kloss, B, Yu, Z, Javitch, J.A, Hendrickson, W.A, Slesinger, P.A, Quick, M, Graziano, J, Yu, H, Fiehn, O, Clarke, O.B, Frank, J, Fan, Q.R. | 登録日 | 2020-04-10 | 公開日 | 2020-07-01 | 最終更新日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of human GABABreceptor in an inactive state. Nature, 584, 2020
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2PK4
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7U6M
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7TVH
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7TJI
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![BU of 7tji by Molmil](/molmil-images/mine/7tji) | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJH
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![BU of 7tjh by Molmil](/molmil-images/mine/7tjh) | S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | 著者 | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | 登録日 | 2022-01-16 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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6WCK
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![BU of 6wck by Molmil](/molmil-images/mine/6wck) | KRAS G-quadruplex G16T mutant with Bromo Uracil replacing T8 and T16. | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*CP*GP*GP*(BRU)P*GP*TP*GP*GP*GP*AP*AP*(BRU)P*AP*GP*GP*GP*AP*A)-3'), POTASSIUM ION | 著者 | Schmidberger, J.W, Ou, A, Smith, N.M, Iyer, K.S, Bond, C.S. | 登録日 | 2020-03-30 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A pi-stacking interactions for small-molecule recognition. Nucleic Acids Res., 48, 2020
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2PHW
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![BU of 2phw by Molmil](/molmil-images/mine/2phw) | Pterocarpus angolensis lectin (PAL) in complex with Man-9 | 分子名称: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Imberty, A, Loris, R. | 登録日 | 2007-04-12 | 公開日 | 2007-07-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | How a plant lectin recognizes high mannose oligosaccharides Plant Physiol., 144, 2007
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3MK1
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![BU of 3mk1 by Molmil](/molmil-images/mine/3mk1) | Refinement of placental alkaline phosphatase complexed with nitrophenyl | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Alkaline phosphatase, ... | 著者 | Stec, B, Cheltsov, A, Millan, J.L. | 登録日 | 2010-04-13 | 公開日 | 2011-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site. Acta Crystallogr.,Sect.F, 66, 2010
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7TLO
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3M4Y
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![BU of 3m4y by Molmil](/molmil-images/mine/3m4y) | Structural characterization of the subunit A mutant P235A of the A-ATP synthase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ... | 著者 | Manimekalai, M.S, Balakrishna, A.M, Kumar, A, Priya, R, Biukovic, G, Jeyakanthan, J, Gruber, G. | 登録日 | 2010-03-12 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | The critical roles of residues P235 and F236 of subunit A of the motor protein A-ATP synthase in P-loop formation and nucleotide binding. J.Mol.Biol., 401, 2010
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2Q0N
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![BU of 2q0n by Molmil](/molmil-images/mine/2q0n) | Structure of human p21 activating kinase 4 (PAK4) in complex with a consensus peptide | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Serine/threonine-protein kinase PAK 4, ... | 著者 | Filippakopoulos, P, Eswaran, J, Turnbull, A, Papagrigoriou, E, Pike, A.W, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C.H, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-22 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of human p21 activating kinase 4 (PAK4) in complex with a consensus peptide. To be Published
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2PHU
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![BU of 2phu by Molmil](/molmil-images/mine/2phu) | Pterocarpus angolensis lectin in complex with Man-8D1D3 | 分子名称: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Imberty, A, Loris, R. | 登録日 | 2007-04-12 | 公開日 | 2007-07-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | How a plant lectin recognizes high mannose oligosaccharides Plant Physiol., 144, 2007
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6ZTG
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![BU of 6ztg by Molmil](/molmil-images/mine/6ztg) | Spor protein DedD | 分子名称: | Cell division protein DedD | 著者 | Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W. | 登録日 | 2020-07-20 | 公開日 | 2020-11-11 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. Mbio, 11, 2020
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2PLW
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![BU of 2plw by Molmil](/molmil-images/mine/2plw) | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). | 分子名称: | Ribosomal RNA methyltransferase, putative, S-ADENOSYLMETHIONINE, ... | 著者 | Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | 登録日 | 2007-04-20 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). To be Published
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2PQ0
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![BU of 2pq0 by Molmil](/molmil-images/mine/2pq0) | Crystal structure of Hyopthetical protein (gk_1056) from geobacillus Kaustophilus HTA426 | 分子名称: | Hypothetical conserved protein GK1056 | 著者 | Kanaujia, S.P, Jeyakanthan, J, Kavyashree, M, Sekar, K, Agari, Y, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-01 | 公開日 | 2008-05-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Hyopthetical protein (gk_1056) from geobacillus Kaustophilus HTA426 To be Published
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2PX7
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![BU of 2px7 by Molmil](/molmil-images/mine/2px7) | Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8 | 分子名称: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase | 著者 | Chen, L, Tsukuda, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chen, L.-Q, Liu, Z.-J, Lee, D, Chang, S.-H, Nguyen, D, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-14 | 公開日 | 2007-06-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8. To be Published
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3MCH
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![BU of 3mch by Molmil](/molmil-images/mine/3mch) | Crystal structure of the molybdopterin biosynthesis enzyme MoaB (TTHA0341) from thermus theromophilus HB8 | 分子名称: | 1,2-ETHANEDIOL, Molybdopterin biosynthesis enzyme, MoaB | 著者 | Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Baba, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-03-29 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal structures, dynamics and functional implications of molybdenum-cofactor biosynthesis protein MogA from two thermophilic organisms Acta Crystallogr.,Sect.F, 67, 2011
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7V0J
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![BU of 7v0j by Molmil](/molmil-images/mine/7v0j) | Crystal structure of a CelR catalytic domain active site mutant with bound cellobiose product | 分子名称: | CALCIUM ION, Glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Bingman, C.A, Kuch, N, Kutsche, M.E, Parker, A, Smith, R.W, Fox, B.G. | 登録日 | 2022-05-10 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Contribution of calcium ligands in substrate binding and product release in the Acetovibrio thermocellus glycoside hydrolase family 9 cellulase CelR. J.Biol.Chem., 299, 2023
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7UNP
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![BU of 7unp by Molmil](/molmil-images/mine/7unp) | Crystal structure of the CelR catalytic domain and CBM3c | 分子名称: | CALCIUM ION, Glucanase | 著者 | Bingman, C.A, Kuch, N, Kutsche, M.E, Parker, A, Smith, R.W, Fox, B.G. | 登録日 | 2022-04-11 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Contribution of calcium ligands in substrate binding and product release in the Acetovibrio thermocellus glycoside hydrolase family 9 cellulase CelR. J.Biol.Chem., 299, 2023
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7V0I
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![BU of 7v0i by Molmil](/molmil-images/mine/7v0i) | Crystal structure of a CelR catalytic domain active site mutant with bound cellohexaose substrate | 分子名称: | CALCIUM ION, Glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Bingman, C.A, Kuch, N, Kutsche, M.E, Parker, A, Smith, R.W, Fox, B.G. | 登録日 | 2022-05-10 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Contribution of calcium ligands in substrate binding and product release in the Acetovibrio thermocellus glycoside hydrolase family 9 cellulase CelR. J.Biol.Chem., 299, 2023
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7V0N
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![BU of 7v0n by Molmil](/molmil-images/mine/7v0n) | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21 | 分子名称: | IgG 21 Fab heavy chain, IgG 21 Fab light chain, Spike glycoprotein E1, ... | 著者 | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | 登録日 | 2022-05-10 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
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6WCE
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![BU of 6wce by Molmil](/molmil-images/mine/6wce) | Structure of the periplasmic binding protein P5PA | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal-5-phosphate binding protein A (P5PA) | 著者 | Pan, C, Zimmer, A, Shah, M, Huynh, M, Lai, C.C.L, Sit, B, Hooda, Y, Moraes, T.F. | 登録日 | 2020-03-30 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.754 Å) | 主引用文献 | Actinobacillus utilizes a binding protein-dependent ABC transporter to acquire the active form of vitamin B 6 . J.Biol.Chem., 297, 2021
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7V0O
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![BU of 7v0o by Molmil](/molmil-images/mine/7v0o) | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-94 | 分子名称: | IgG 94 Fab heavy chain, IgG 94 Fab light chain, Spike glycoprotein E1, ... | 著者 | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | 登録日 | 2022-05-10 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 120, 2023
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