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PDB: 17 results

5K4H
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BU of 5k4h by Molmil
Wolinella succinogenes L-asparaginase S121 + L-Glutamic acid
Descriptor: GLUTAMIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lave, A.
Deposit date:2016-05-20
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5K4G
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BU of 5k4g by Molmil
Wolinella succinogenes L-asparaginase S121 + L-aspartic acid, open conformation
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lave, A.
Deposit date:2016-05-20
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5HW0
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BU of 5hw0 by Molmil
Erwinia chrysanthemi L-asparaginase + Glutamic acid
Descriptor: GLUTAMIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lavie, A.
Deposit date:2016-01-28
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
5I4B
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BU of 5i4b by Molmil
Erwinia chrysanthemi L-asparaginase E63Q +S254N mutation + L-Aspartic acid
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lavie, A.
Deposit date:2016-02-11
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
5I3Z
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BU of 5i3z by Molmil
Erwinia chrysanthemi L-asparaginase E63Q mutation + Aspartic acid
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lavie, A.
Deposit date:2016-02-11
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
5I48
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BU of 5i48 by Molmil
Erwinia chrysanthemi L-asparaginase A31I + E63Q mutation + Aspartic acid
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lavie, A.
Deposit date:2016-02-11
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
5K3O
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BU of 5k3o by Molmil
Wolinella succinogenes L-asparaginase P121 and L-Aspartic acid
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lave, A.
Deposit date:2016-05-19
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5K45
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BU of 5k45 by Molmil
Wolinella succinogenes L-asparaginase P121 + L-Glutamic acid
Descriptor: GLUTAMIC ACID, L-asparaginase
Authors:Nguyen, H.A, Lave, A.
Deposit date:2016-05-20
Release date:2017-03-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5F52
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BU of 5f52 by Molmil
Erwinia chrysanthemi L-asparaginase + Aspartic acid
Descriptor: ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, L-asparaginase
Authors:Nguyen, H.A, Lavie, A.
Deposit date:2015-12-04
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
6OF6
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BU of 6of6 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Sunita, S, Dunham, C.M.
Deposit date:2019-03-28
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OPE
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BU of 6ope by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Sunita, S, Dunham, C.M.
Deposit date:2019-04-24
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
8FOM
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BU of 8fom by Molmil
Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2023-01-02
Release date:2023-03-29
Last modified:2023-04-26
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FON
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BU of 8fon by Molmil
Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2023-01-02
Release date:2023-03-29
Last modified:2023-04-26
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
6ORD
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BU of 6ord by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Sunita, S, Dunham, C.M.
Deposit date:2019-04-30
Release date:2020-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OJ2
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BU of 6oj2 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Sunita, S, Dunham, C.M.
Deposit date:2019-04-10
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
Descriptor: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
Deposit date:2023-01-06
Release date:2023-09-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
7U6M
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BU of 7u6m by Molmil
Albumin binding domain fused to a mutant of the Erwinia asparaginase
Descriptor: ASPARTIC ACID, L-asparaginase
Authors:Lavie, A, Nguyen, H.A.
Deposit date:2022-03-04
Release date:2022-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia.
Haematologica, 108, 2023

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