7TVH

Hyperlytic variant of Tae1, Type VI secretion amidase effector 1, from Pseudomonas aeruginosa (Cys110Ser)

Summary for 7TVH

Entry DOI	10.2210/pdb7tvh/pdb
Descriptor	Peptidoglycan amidase Tse1 (2 entities in total)
Functional Keywords	type vi secretion amidase effector, tae1 hyperlytic variant, cys110ser, antimicrobial protein, hydrolase
Biological source	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains	4
Total formula weight	70055.05
Authors	Radkov, A.,Saunders, H.,Chou, S. (deposition date: 2022-02-04, release date: 2022-07-06, Last modification date: 2023-10-25)
Primary citation	Radkov, A.,Sapiro, A.L.,Flores, S.,Henderson, C.,Saunders, H.,Kim, R.,Massa, S.,Thompson, S.,Mateusiak, C.,Biboy, J.,Zhao, Z.,Starita, L.M.,Hatleberg, W.L.,Vollmer, W.,Russell, A.B.,Simorre, J.P.,Anthony-Cahill, S.,Brzovic, P.,Hayes, B.,Chou, S. Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context. Elife, 11:-, 2022 Cited by PubMed: 35762582 DOI: 10.7554/eLife.79796 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation