6ELA
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![BU of 6ela by Molmil](/molmil-images/mine/6ela) | Crystal structure of MMP12 in complex with inhibitor BE4. | 分子名称: | (2~{S})-2-[2-[4-(4-methoxyphenyl)phenyl]sulfanylphenyl]pentanedioic acid, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... | 著者 | Ciccone, L, Tepshi, L, Nuti, E, Rossello, A, Stura, E.A. | 登録日 | 2017-09-28 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.485 Å) | 主引用文献 | Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies. J. Med. Chem., 61, 2018
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6EKN
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![BU of 6ekn by Molmil](/molmil-images/mine/6ekn) | Crystal structure of MMP12 in complex with inhibitor BE7. | 分子名称: | (2~{S})-2-[2-[4-(4-methoxyphenyl)phenyl]sulfonylphenyl]pentanedioic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Ciccone, L, Tepshi, L, Nuti, E, Rossello, A, Stura, E.A. | 登録日 | 2017-09-26 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies. J. Med. Chem., 61, 2018
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1TL5
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![BU of 1tl5 by Molmil](/molmil-images/mine/1tl5) | Solution structure of apoHAH1 | 分子名称: | Copper transport protein ATOX1 | 著者 | Anastassopoulou, I, Banci, L, Bertini, I, Cantini, F, Katsari, E, Rosato, A, Structural Proteomics in Europe (SPINE) | 登録日 | 2004-06-09 | 公開日 | 2004-10-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Apo and Copper(I)-Loaded Human Metallochaperone HAH1. Biochemistry, 43, 2004
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5E4O
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![BU of 5e4o by Molmil](/molmil-images/mine/5e4o) | Human transthyretin (TTR) complexed with (Z)-((3,4-Dichloro-phenyl)-methyleneaminooxy)-acetic acid | 分子名称: | ({(Z)-[(3,4-dichlorophenyl)(phenyl)methylidene]amino}oxy)acetic acid, Transthyretin | 著者 | Ciccone, L, Savko, M, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | 登録日 | 2015-10-06 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR). J Enzyme Inhib Med Chem, 31, 2016
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5E23
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![BU of 5e23 by Molmil](/molmil-images/mine/5e23) | Human transthyretin (TTR) complexed with (2,7-Dibromo-fluoren-9-ylideneaminooxy)-acetic acid | 分子名称: | DIMETHYL SULFOXIDE, Transthyretin, {[(2,7-dibromo-9H-fluoren-9-ylidene)amino]oxy}acetic acid | 著者 | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | 登録日 | 2015-09-30 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR). J Enzyme Inhib Med Chem, 31, 2016
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1J6Q
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![BU of 1j6q by Molmil](/molmil-images/mine/1j6q) | Solution structure and characterization of the heme chaperone CcmE | 分子名称: | cytochrome c maturation protein E | 著者 | Arnesano, F, Banci, L, Barker, P.D, Bertini, I, Rosato, A, Su, X.C, Viezzoli, M.S. | 登録日 | 2002-04-30 | 公開日 | 2002-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and characterization of the heme chaperone CcmE Biochemistry, 41, 2002
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1JAS
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![BU of 1jas by Molmil](/molmil-images/mine/1jas) | HsUbc2b | 分子名称: | UBIQUITIN-CONJUGATING ENZYME E2-17 KDA | 著者 | Miura, T, Klaus, W, Ross, A, Guentert, P, Senn, H. | 登録日 | 2001-05-31 | 公開日 | 2003-09-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The NMR structure of the class I human ubiquitin-conjugating enzyme 2b J.Biomol.NMR, 22, 2002
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1KX2
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![BU of 1kx2 by Molmil](/molmil-images/mine/1kx2) | Minimized average structure of a mono-heme ferrocytochrome c from Shewanella putrefaciens | 分子名称: | HEME C, mono-heme c-type cytochrome ScyA | 著者 | Bartalesi, I, Bertini, I, Hajieva, P, Rosato, A, Vasos, P.R. | 登録日 | 2002-01-30 | 公開日 | 2002-02-13 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a monoheme ferrocytochrome c from Shewanella putrefaciens and structural analysis of sequence-similar proteins: functional implications. Biochemistry, 41, 2002
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1KX7
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![BU of 1kx7 by Molmil](/molmil-images/mine/1kx7) | Family of 30 conformers of a mono-heme ferrocytochrome c from Shewanella putrefaciens solved by NMR | 分子名称: | HEME C, mono-heme c-type cytochrome ScyA | 著者 | Bartalesi, I, Bertini, I, Hajieva, P, Rosato, A, Vasos, P.R. | 登録日 | 2002-01-31 | 公開日 | 2002-02-13 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a monoheme ferrocytochrome c from Shewanella putrefaciens and structural analysis of sequence-similar proteins: functional implications. Biochemistry, 41, 2002
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1S6O
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![BU of 1s6o by Molmil](/molmil-images/mine/1s6o) | Solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the Menkes protein ATP7A | 分子名称: | Copper-transporting ATPase 1 | 著者 | Banci, L, Bertini, I, Del Conte, R, D'Onofrio, M, Rosato, A, Structural Proteomics in Europe (SPINE) | 登録日 | 2004-01-26 | 公開日 | 2004-04-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Backbone Dynamics of the Cu(I) and Apo Forms of the Second Metal-Binding Domain of the Menkes Protein ATP7A. Biochemistry, 43, 2004
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1KLK
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![BU of 1klk by Molmil](/molmil-images/mine/1klk) | CRYSTAL STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH PT653 AND NADPH | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Rosowsky, A, Queener, S.F. | 登録日 | 2001-12-12 | 公開日 | 2002-12-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH. Acta Crystallogr.,Sect.D, 58, 2002
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1S6U
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![BU of 1s6u by Molmil](/molmil-images/mine/1s6u) | Solution structure and backbone dynamics of the Cu(I) form of the second metal-binding domain of the Menkes protein ATP7A | 分子名称: | COPPER (I) ION, Copper-transporting ATPase 1 | 著者 | Banci, L, Bertini, I, Del Conte, R, D'Onofrio, M, Rosato, A, Structural Proteomics in Europe (SPINE) | 登録日 | 2004-01-27 | 公開日 | 2004-04-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Backbone Dynamics of the Cu(I) and Apo Forms of the Second Metal-Binding Domain of the Menkes Protein ATP7A. Biochemistry, 43, 2004
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2BOC
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![BU of 2boc by Molmil](/molmil-images/mine/2boc) | Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs) | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | 著者 | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | 登録日 | 2005-04-09 | 公開日 | 2005-04-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Structural Basis of Tea Blockade in a Model Potassium Channel Nat.Struct.Mol.Biol., 12, 2005
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2BOB
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![BU of 2bob by Molmil](/molmil-images/mine/2bob) | Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA) | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | 著者 | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | 登録日 | 2005-04-09 | 公開日 | 2005-04-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural Basis of Tea Blockade in a Model Potassium Channel Nat.Struct.Mol.Biol., 12, 2005
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1LM0
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![BU of 1lm0 by Molmil](/molmil-images/mine/1lm0) | Solution structure and characterization of the heme chaperone CcmE | 分子名称: | cytochrome c maturation protein E | 著者 | Arnesano, F, Banci, L, Barker, P.D, Bertini, I, Rosato, A, Su, X.C, Viezzoli, M.S. | 登録日 | 2002-04-30 | 公開日 | 2002-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and characterization of the heme chaperone CcmE Biochemistry, 41, 2002
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1MCX
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1KFO
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![BU of 1kfo by Molmil](/molmil-images/mine/1kfo) | CRYSTAL STRUCTURE OF AN RNA HELIX RECOGNIZED BY A ZINC-FINGER PROTEIN: AN 18 BASE PAIR DUPLEX AT 1.6 RESOLUTION | 分子名称: | 5'-R(*GP*AP*AP*UP*GP*CP*CP*UP*GP*CP*GP*AP*GP*CP*AP*(5BU)P*CP*CP*C)-3' | 著者 | Lima, S, Hildenbrand, J, Korostelev, A, Hattman, S, Li, H. | 登録日 | 2001-11-21 | 公開日 | 2001-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of an RNA helix recognized by a zinc-finger protein: an 18-bp duplex at 1.6 A resolution. RNA, 8, 2002
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2W0F
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![BU of 2w0f by Molmil](/molmil-images/mine/2w0f) | Potassium Channel KcsA-Fab Complex with Tetraoctylammonium | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | 著者 | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | 登録日 | 2008-08-14 | 公開日 | 2009-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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2X2Y
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![BU of 2x2y by Molmil](/molmil-images/mine/2x2y) | Cellulomonas fimi endo-beta-1,4-mannanase double mutant | 分子名称: | FORMIC ACID, MAGNESIUM ION, MAN26A | 著者 | Hekmat, O, Lo Leggio, L, Rosengren, A, Kamarauskaite, J, Kolenova, K, Staalbrand, H. | 登録日 | 2010-01-18 | 公開日 | 2010-06-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Rational Engineering of Mannosyl Binding in the Distal Glycone Subsites of Cellulomonas Fimi Endo-Beta-1,4-Mannanase: Mannosyl Binding Promoted at Subsite -2 and Demoted at Subsite -3 . Biochemistry, 49, 2010
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1OKD
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![BU of 1okd by Molmil](/molmil-images/mine/1okd) | NMR-structure of tryparedoxin 1 | 分子名称: | TRYPAREDOXIN 1 | 著者 | Krumme, D, Budde, H, Hecht, H.-J, Menge, U, Ohlenschlager, O, Ross, A, Wissing, J, Wray, V, Flohe, L. | 登録日 | 2003-07-22 | 公開日 | 2003-08-28 | 最終更新日 | 2018-01-17 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues. Biochemistry, 42, 2003
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2XYF
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![BU of 2xyf by Molmil](/molmil-images/mine/2xyf) | HIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime Substituents | 分子名称: | METHYL N-[(2S)-1-[2-[(4R)-5-[[(2S)-3,3-DIMETHYL-1-METHYLAMINO-1-OXO-BUTAN-2-YL]AMINO]-4-HYDROXY-5-OXO-4-(PHENYLMETHYL)PENTYL]-2-[(4-THIOPHEN-3-YLPHENYL)METHYL]HYDRAZINYL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE, PROTEASE | 著者 | Ohrngren, P, Wu, X, Persson, M, Ekegren, J.K, Wallberg, H, Rosenquist, A, Samuelsson, B, Unge, T, Larhed, M. | 登録日 | 2010-11-17 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | HIV-1 Protease Inhibitors with a Tertiary Alcohol Containing Transition-State Mimic and Various P2 and P1' Substituents Med.Chem.Commun., 2, 2011
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1QPU
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![BU of 1qpu by Molmil](/molmil-images/mine/1qpu) | SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | 分子名称: | CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R. | 登録日 | 1999-05-30 | 公開日 | 1999-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999
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2XYE
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![BU of 2xye by Molmil](/molmil-images/mine/2xye) | HIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime Substituents | 分子名称: | METHYL N-[(2S)-1-[2-[(4R)-5-[[(2S)-3,3-DIMETHYL-1-METHYLAMINO-1-OXO-BUTAN-2-YL]AMINO]-4-HYDROXY-5-OXO-4-(PHENYLMETHYL)PENTYL]-2-[(4-PHENYLPHENYL)METHYL]HYDRAZINYL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE, PROTEASE | 著者 | Ohrngren, P, Wu, X, Persson, M, Ekegren, J.K, Wallberg, H, Rosenquist, A, Samuelsson, B, Unge, T, Larhed, M. | 登録日 | 2010-11-17 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | HIV-1 Protease Inhibitors with a Tertiary Alcohol Containing Transition-State Mimic and Various P2 and P1' Substituents Med.Chem.Commun., 2, 2011
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2FZI
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![BU of 2fzi by Molmil](/molmil-images/mine/2fzi) | New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives | 分子名称: | 2,4-DIAMINO-5-[3',4'-DIMETHOXY-5'-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Chisum, K, Rosowsky, A. | 登録日 | 2006-02-09 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins, 65, 2006
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2FZH
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![BU of 2fzh by Molmil](/molmil-images/mine/2fzh) | New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives | 分子名称: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Chisum, K, Rosowsky, A. | 登録日 | 2006-02-09 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins, 65, 2006
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