2ZJ4
 
 | | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | | 分子名称: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | | 著者 | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | | 登録日 | 2008-02-29 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
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3A8H
 | | Crystal structure of Nitrile Hydratase mutant S113A complexed with Trimethylacetamide | | 分子名称: | 2,2-dimethylpropanamide, FE (III) ION, Nitrile hydratase subunit alpha, ... | | 著者 | Yamanaka, Y, Hashimoto, K, Ohtaki, A, Noguchi, K, Yohda, M, Odaka, M. | | 登録日 | 2009-10-06 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
J.Biol.Inorg.Chem., 15, 2010
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2ZJ3
 | | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | | 著者 | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | | 登録日 | 2008-02-29 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
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3A8O
 | | Crystal structure of Nitrile Hydratase complexed with Trimethylacetamide | | 分子名称: | 2,2-dimethylpropanamide, FE (III) ION, Nitrile hydratase subunit alpha, ... | | 著者 | Yamanaka, Y, Hashimoto, K, Ohtaki, A, Noguchi, K, Yohda, M, Odaka, M. | | 登録日 | 2009-10-07 | | 公開日 | 2010-04-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
J.Biol.Inorg.Chem., 15, 2010
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3WKR
 | | Crystal structure of the SepCysS-SepCysE complex from Methanocaldococcus jannaschii | | 分子名称: | O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481 | | 著者 | Nakazawa, Y, Asano, N, Nakamura, A, Yao, M. | | 登録日 | 2013-10-30 | | 公開日 | 2014-07-16 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WKS
 | | Crystal structure of the SepCysS-SepCysE N-terminal domain complex from | | 分子名称: | O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481 | | 著者 | Nakazawa, Y, Asano, N, Nakamura, A, Yao, M. | | 登録日 | 2013-10-30 | | 公開日 | 2014-07-30 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (3.029 Å) | | 主引用文献 | Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3IS1
 | | Crystal structure of functional region of UafA from Staphylococcus saprophyticus in C2 form at 2.45 angstrom resolution | | 分子名称: | GLYCEROL, Uro-adherence factor A | | 著者 | Tanaka, Y, Matsuoka, E, Shouji, Y, Kuroda, M, Tanaka, I, Yao, M. | | 登録日 | 2009-08-24 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
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3IS0
 | | Crystal structure of functional region of UafA from Staphylococcus saprophyticus in the presence of cholesterol | | 分子名称: | GLYCEROL, Uro-adherence factor A | | 著者 | Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M. | | 登録日 | 2009-08-24 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of Functional Region of UafA from Staphylococcus saprophyticus
To be Published
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3IRP
 | | Crystal structure of functional region of UafA from Staphylococcus saprophyticus at 1.50 angstrom resolution | | 分子名称: | GLYCEROL, POTASSIUM ION, Uro-adherence factor A | | 著者 | Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M. | | 登録日 | 2009-08-24 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
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3IRZ
 | | Crystal structure of functional region of UafA from Staphylococcus saprophyticus in P212121 form | | 分子名称: | GLYCEROL, Uro-adherence factor A | | 著者 | Tanaka, Y, Shouji, Y, Matsuoka, E, Kuroda, M, Tanaka, I, Yao, M. | | 登録日 | 2009-08-24 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
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2DVQ
 | | Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide | | 分子名称: | Bromodomain-containing protein 2, histone H4 | | 著者 | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain.
J.Biol.Chem., 285, 2010
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2DVR
 | | Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide | | 分子名称: | bromodomain-containing protein 2, histone H4 | | 著者 | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain.
J.Biol.Chem., 285, 2010
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6YYW
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | | 分子名称: | 2-OXOGLUTARIC ACID, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-05-06 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase.
Chem Sci, 12, 2020
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6YYY
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 4,4-dimethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | | 分子名称: | 2,2-dimethyl-4-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-05-06 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase.
Chem Sci, 12, 2020
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6Z6Q
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-ethyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | | 分子名称: | (3~{R})-3-ethyl-2-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-05-29 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase.
Chem Sci, 12, 2020
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6YYV
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6Z6R
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, N-oxalyl-alpha-methylalanine, and factor X substrate peptide fragment(39mer-4Ser) | | 分子名称: | Aspartyl/asparaginyl beta-hydroxylase, BROMIDE ION, Coagulation factor X, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-05-29 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase.
Chem Sci, 12, 2020
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6YYU
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6YYX
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-methyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser) | | 分子名称: | (3~{R})-3-methyl-2-oxidanylidene-pentanedioic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | | 著者 | Nakashima, Y, Brewitz, L, Schofield, C.J. | | 登録日 | 2020-05-06 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase
Chem Sci, 12, 2021
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6RUJ
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2DVS
 | | Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide | | 分子名称: | bromodomain-containing protein 2, histone H4 | | 著者 | Nakamura, Y, Umehara, T, Shirouzu, M, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-08-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain.
J.Biol.Chem., 285, 2010
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8II0
 | | FACTOR INHIBITING HIF-1 ALPHA in complex with (5-(3-(3-chlorophenyl)isoxazol-5-yl)-3-hydroxypicolinoyl)glycine | | 分子名称: | 2-[[5-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | | 著者 | Nakashima, Y, Corner, T, Zhang, X, Schofield, C.J. | | 登録日 | 2023-02-24 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-flip Pocket for the Treatment of Obesity.
Angew.Chem.Int.Ed.Engl., 2024
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8IHZ
 | | FACTOR INHIBITING HIF-1 ALPHA in complex with (5-(1-(3-(4-chlorophenyl)propyl)-1H-1,2,3-triazol-4-yl)-3-hydroxypicolinoyl)glycine | | 分子名称: | 2-[[5-[1-[3-(4-chlorophenyl)propyl]-1,2,3-triazol-4-yl]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid, Hypoxia-inducible factor 1-alpha inhibitor, SULFATE ION, ... | | 著者 | Nakashima, Y, Corner, T, Zhang, X, Schofield, C.J. | | 登録日 | 2023-02-24 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-flip Pocket for the Treatment of Obesity.
Angew.Chem.Int.Ed.Engl., 2024
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1WVT
 | | Crystal structure of uncharacterized protein ST2180 from Sulfolobus tokodaii | | 分子名称: | hypothetical protein ST2180 | | 著者 | Sasaki, T, Tanaka, Y, Yasutake, Y, Tsumoto, K, Tanaka, I, Kumagai, I. | | 登録日 | 2004-12-27 | | 公開日 | 2006-01-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular properties of two proteins homologous to PduO-type ATP:cob(I)alamin adenosyltransferase from Sulfolobus tokodaii
Proteins, 68, 2007
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3O6A
 | | F144Y/F258Y Double Mutant of Exo-beta-1,3-glucanase from Candida albicans at 2 A | | 分子名称: | Glucan 1,3-beta-glucosidase | | 著者 | Nakatani, Y, Cutfield, S.M, Cutfield, J.F. | | 登録日 | 2010-07-28 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance
Febs J., 277, 2010
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