6RUJ

Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)3-hydroxy-Leu peptide

Summary for 6RUJ

• Entry DOI: 10.2210/pdb6ruj/pdb
• Related: 4NR1
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)3-hydroxy-Leu, ZINC ION, ... (6 entities in total)
• Functional Keywords: 2-og-dependent dioxygenase, oxidoreductase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 42452.85

Authors

Nakashima, Y.,McDonough, M.A.,Schofield, C.J. (deposition date: 2019-05-28, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Choi, H.,Hardy, A.,Leissing, T.M.,Chowdhury, R.,Ge, W.,Markoulides, M.,Scotti, J.S.,Thorbjornsrud, H.,Nakashima, Y.,Kang, D.,Hong, S.,Lee, J.,Park, H.,McDonough, M.A.,Schofield, C.J.; A human protein hydroxylase that accepts D-residues; Commun Chem, 2020; DOI: 10.1038/s42004-020-0290-5

Experimental method

X-RAY DIFFRACTION (2.42 Å)