6YYX
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-methyl-2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)
Summary for 6YYX
Entry DOI | 10.2210/pdb6yyx/pdb |
Descriptor | Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 53810.78 |
Authors | Nakashima, Y.,Brewitz, L.,Schofield, C.J. (deposition date: 2020-05-06, release date: 2021-03-17, Last modification date: 2024-01-24) |
Primary citation | Brewitz, L.,Nakashima, Y.,Schofield, C.J. Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase Chem Sci, 12:1327-1342, 2021 Cited by DOI: 10.1039/D0SC04301JPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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