1G1F
 
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A TRI-PHOSPHORYLATED PEPTIDE (RDI(PTR)ETD(PTR)(PTR)RK) FROM THE INSULIN RECEPTOR KINASE | | 分子名称: | PROTEIN TYROSINE PHOSPHATASE 1B, TRI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE | | 著者 | Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D. | | 登録日 | 2000-10-11 | | 公開日 | 2001-01-17 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
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2XPI
 | | Crystal structure of APC/C hetero-tetramer Cut9-Hcn1 | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT CUT9, ANAPHASE-PROMOTING COMPLEX SUBUNIT HCN1 HCN1/CDC26,20S CYCLOSOME/APC COMPLEX PROTEIN HCN1, CHAPERONE-LIKE PROTEIN HCN1, ... | | 著者 | Zhang, Z, Kulkarni, K.A, Barford, D. | | 登録日 | 2010-08-26 | | 公開日 | 2011-03-30 | | 最終更新日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Apc/C Subunit Cdc16/Cut9 is a Contiguous Tetratricopeptide Superhelix with a Homo-Dimer Interface Similar to Cdc27
Embo J., 29, 2010
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2UW4
 | | Structure of PKA-PKB chimera complexed with 2-(4-(5-methyl-1H-pyrazol- 4-yl)-phenyl)-ethylamine | | 分子名称: | 2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... | | 著者 | Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A. | | 登録日 | 2007-03-19 | | 公開日 | 2007-05-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery
J.Med.Chem., 50, 2007
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2UW5
 | | Structure of PKA-PKB chimera complexed with (R)-2-(4-chloro-phenyl)- 2-(4-1H-pyrazol-4-yl)-phenyl)-ethylamine | | 分子名称: | (2R)-2-(4-CHLOROPHENYL)-2-[4-(1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... | | 著者 | Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A. | | 登録日 | 2007-03-19 | | 公開日 | 2007-05-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery
J.Med.Chem., 50, 2007
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2UW7
 | | Structure of PKA-PKB chimera complexed with 4-(4-chloro-phenyl)-4-(4- (1H-pyrazol-4-yl)-phenyl)-piperidine | | 分子名称: | 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... | | 著者 | Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A. | | 登録日 | 2007-03-19 | | 公開日 | 2007-05-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery
J.Med.Chem., 50, 2007
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1G1G
 | | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A MONO-PHOSPHORYLATED PEPTIDE (ETDY(PTR)RKGGKGLL) FROM THE INSULIN RECEPTOR KINASE | | 分子名称: | MONO-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE, PROTEIN TYROSINE PHOSPHATASE 1B | | 著者 | Salmeen, A, Andersen, J.N, Myers, M.P, Tonks, N.K, Barford, D. | | 登録日 | 2000-10-11 | | 公開日 | 2001-01-17 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
Mol.Cell, 6, 2000
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2VFY
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1HKO
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2V0P
 | | The Structure of Tap42 Alpha4 Subunit | | 分子名称: | TYPE 2A PHOSPHATASE-ASSOCIATED PROTEIN 42, ZINC ION | | 著者 | Roe, S.M, Yang, J, Barford, D. | | 登録日 | 2007-05-15 | | 公開日 | 2007-07-17 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Structure of Tap42/Alpha4 Reveals a Tetratricopeptide Repeat-Like Fold and Provides Insights Into Pp2A Regulation.
Biochemistry, 46, 2007
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6GBY
 | | Copper nitrite reductase from Achromobacter cycloclastes: non-polymorph separated dataset 1 | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION | | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | | 登録日 | 2018-04-16 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 75, 2019
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6GBB
 | | Copper nitrite reductase from Achromobacter cycloclastes: large cell polymorph dataset 1 | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION | | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | | 登録日 | 2018-04-13 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 75, 2019
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6GCG
 | | Copper nitrite reductase from Achromobacter cycloclastes: large polymorph dataset 15 | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase | | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | | 登録日 | 2018-04-17 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.80015242 Å) | | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 75, 2019
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6GUX
 | | Dark-adapted structure of Archaerhodopsin-3 at 100K | | 分子名称: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Moraes, I, Judge, P.J, Bada Juarez, J.F, Vinals, J, Axford, D, Watts, A. | | 登録日 | 2018-06-19 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization.
Nat Commun, 12, 2021
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6GUZ
 | | Ground state structure of Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich at room temperature | | 分子名称: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Moraes, I, Judge, P.J, Bada Juarez, J.F, Vinals, J, Axford, D, Watts, A. | | 登録日 | 2018-06-19 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Room temperature structure of the Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich
To Be Published
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1OHC
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1QMW
 | | Solution structure of alpha-conotoxin SI | | 分子名称: | ALPHA-CONOTOXIN SI | | 著者 | Benie, A.J, Whitford, D, Hargittai, B, Barany, G, Janes, R.W. | | 登録日 | 1999-10-08 | | 公開日 | 2000-08-25 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Alpha-Conotoxin Si
FEBS Lett., 476, 2000
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1O6K
 | | Structure of activated form of PKB kinase domain S474D with GSK3 peptide and AMP-PNP | | 分子名称: | GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D. | | 登録日 | 2002-10-08 | | 公開日 | 2002-11-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
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1O6L
 | | Crystal structure of an activated Akt/protein kinase B (PKB-PIF chimera) ternary complex with AMP-PNP and GSK3 peptide | | 分子名称: | GLYCOGEN SYNTHASE KINASE-3 BETA, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Yang, J, Cron, P, Good, V.M, Thompson, V, Hemmings, B.A, Barford, D. | | 登録日 | 2002-10-08 | | 公開日 | 2002-11-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of an Activated Akt/Protein Kinase B Ternary Complex with Gsk-3 Peptide and AMP-Pnp
Nat.Struct.Biol., 9, 2002
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1OHD
 | | structure of cdc14 in complex with tungstate | | 分子名称: | CDC14B2 PHOSPHATASE, TUNGSTATE(VI)ION | | 著者 | Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. | | 登録日 | 2003-05-24 | | 公開日 | 2003-07-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
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1OHE
 | | Structure of cdc14b phosphatase with a peptide ligand | | 分子名称: | CDC14B2 PHOSPHATASE, PEPTIDE LIGAND | | 著者 | Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. | | 登録日 | 2003-05-24 | | 公開日 | 2003-07-24 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Embo J., 22, 2003
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7NJ0
 | | CryoEM structure of the human Separase-Cdk1-cyclin B1-Cks1 complex | | 分子名称: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1, G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B1, ... | | 著者 | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | | 登録日 | 2021-02-14 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Nature, 596, 2021
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7NJ1
 | | CryoEM structure of the human Separase-Securin complex | | 分子名称: | Securin, Separin | | 著者 | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | | 登録日 | 2021-02-14 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Nature, 596, 2021
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6GUY
 | | Room temperature structure of Archaerhodopsin-3 via LCP extruder using synchrotron radiation | | 分子名称: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Moraes, I, Judge, P.J, Axford, D, Bada Juarez, J.F, Vinals, J, Watts, A. | | 登録日 | 2018-06-19 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Room temperature structure of Archaerhodopsin-3 via LCP extruder using synchrotron radiation
To Be Published
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6TM5
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6GB8
 | | Copper nitrite reductase from Achromobacter cycloclastes: small cell polymorph dataset 1 | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION | | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | | 登録日 | 2018-04-13 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography.
Acta Crystallogr D Struct Biol, 75, 2019
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