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7Y1M
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BU of 7y1m by Molmil
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7Y1N
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BU of 7y1n by Molmil
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ...
著者Chen, L, Ding, D, Hou, T.
登録日2022-06-08
公開日2023-06-14
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix.
Nat Commun, 14, 2023
7YNK
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BU of 7ynk by Molmil
Structure of human SGLT2-MAP17 complex in the apo state in the inward-facing conformation
分子名称: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2
著者Chen, L, Niu, Y.
登録日2022-07-31
公開日2023-05-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNJ
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BU of 7ynj by Molmil
Structure of human SGLT2-MAP17 complex bound with substrate AMG in the occluded conformation
分子名称: PDZK1-interacting protein 1, Sodium/glucose cotransporter 2, methyl alpha-D-glucopyranoside
著者Chen, L, Niu, Y, Cui, W.
登録日2022-07-31
公開日2023-05-31
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7YNI
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BU of 7yni by Molmil
Structure of human SGLT1-MAP17 complex bound with substrate 4D4FDG in the occluded conformation
分子名称: (2R,3R,4R,5S,6R)-5-fluoranyl-6-(hydroxymethyl)oxane-2,3,4-triol, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1
著者Chen, L, Niu, Y, Cui, W.
登録日2022-07-31
公開日2023-05-31
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structures of human SGLT in the occluded state reveal conformational changes during sugar transport.
Nat Commun, 14, 2023
7VSI
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BU of 7vsi by Molmil
Structure of human SGLT2-MAP17 complex bound with empagliflozin
分子名称: (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, PALMITIC ACID, PDZK1-interacting protein 1, ...
著者Chen, L, Niu, Y, Liu, R.
登録日2021-10-26
公開日2021-12-15
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter.
Nature, 601, 2022
5YX9
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BU of 5yx9 by Molmil
Cryo-EM structure of human TRPC6 at 3.8A resolution
分子名称: Short transient receptor potential channel 6
著者Chen, L, Tang, Q, Guo, W.
登録日2017-12-02
公開日2018-05-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.
Cell Res., 28, 2018
5ZBG
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BU of 5zbg by Molmil
Cryo-EM structure of human TRPC3 at 4.36A resolution
分子名称: Short transient receptor potential channel 3
著者Chen, L, Tang, Q, Guo, W.
登録日2018-02-11
公開日2018-05-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献Structure of the receptor-activated human TRPC6 and TRPC3 ion channels
Cell Res., 28, 2018
7Y4S
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BU of 7y4s by Molmil
Structure of human MG53 homo-dimer
分子名称: Tripartite motif-containing protein 72
著者Chen, L, Niu, Y.
登録日2022-06-16
公開日2022-09-21
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of human MG53 homodimer.
Biochem.J., 479, 2022
7E3X
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BU of 7e3x by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase
著者Chen, L, Tang, J, Yuan, S, Zhang, F, Chen, S.
登録日2021-02-09
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
8J1N
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BU of 8j1n by Molmil
Structure of human UCP1 in the DNP-bound state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,4-DINITROPHENOL, CARDIOLIPIN, ...
著者Chen, L, Kang, Y.
登録日2023-04-13
公開日2023-06-21
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structural basis for the binding of DNP and purine nucleotides onto UCP1.
Nature, 620, 2023
7VLT
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BU of 7vlt by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP and levcromakalim
分子名称: (3S,4R)-2,2-dimethyl-3-oxidanyl-4-(2-oxidanylidenepyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLR
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BU of 7vlr by Molmil
Structure of SUR2B in complex with Mg-ATP/ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLU
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BU of 7vlu by Molmil
Structure of SUR2A in complex with Mg-ATP/ADP and P1075
分子名称: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
7VLS
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BU of 7vls by Molmil
Structure of SUR2B in complex with MgATP/ADP and P1075
分子名称: 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Chen, L, Ding, D.
登録日2021-10-05
公開日2022-05-18
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural identification of vasodilator binding sites on the SUR2 subunit.
Nat Commun, 13, 2022
5YKF
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BU of 5ykf by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKG
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BU of 5ykg by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.57 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKE
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BU of 5yke by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW9
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BU of 5yw9 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWC
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BU of 5ywc by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWB
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BU of 5ywb by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-30
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW8
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BU of 5yw8 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5Z1F
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BU of 5z1f by Molmil
Structure of atOSCA3.1 channel
分子名称: CSC1-like protein ERD4
著者Chen, L, Zhang, M, Kang, Y, Wu, J.X.
登録日2017-12-26
公開日2018-09-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structure of the mechanosensitive OSCA channels.
Nat. Struct. Mol. Biol., 25, 2018
5YWD
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BU of 5ywd by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW7
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BU of 5yw7 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018

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