7YNI
Structure of human SGLT1-MAP17 complex bound with substrate 4D4FDG in the occluded conformation
Summary for 7YNI
Entry DOI | 10.2210/pdb7yni/pdb |
EMDB information | 33962 |
Descriptor | Sodium/glucose cotransporter 1, PDZK1-interacting protein 1, (2R,3R,4R,5S,6R)-5-fluoranyl-6-(hydroxymethyl)oxane-2,3,4-triol (3 entities in total) |
Functional Keywords | glucose transporter, sglt, sodium glucose transporter, membrane protein, protein transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 85974.85 |
Authors | |
Primary citation | Cui, W.,Niu, Y.,Sun, Z.,Liu, R.,Chen, L. Structures of human SGLT in the occluded state reveal conformational changes during sugar transport. Nat Commun, 14:2920-2920, 2023 Cited by PubMed: 37217492DOI: 10.1038/s41467-023-38720-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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