4NCC
| Neutralizing antibody to murine norovirus | 分子名称: | Fab fragment heavy, Fab fragment light | 著者 | Smith, T, Li, M. | 登録日 | 2013-10-24 | 公開日 | 2014-02-19 | 最終更新日 | 2014-04-09 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization. J.Virol., 88, 2014
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4P59
| HER3 extracellular domain in complex with Fab fragment of MOR09825 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOR09825 Fab fragment heavy chain, ... | 著者 | Sprague, E.R. | 登録日 | 2014-03-15 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res., 73, 2013
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4P73
| PheRS in complex with compound 1a | 分子名称: | 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit | 著者 | Ferguson, A.D. | 登録日 | 2014-03-25 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. J.Biol.Chem., 289, 2014
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4MWF
| Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | 著者 | Kong, L, Wilson, I.A, Law, M. | 登録日 | 2013-09-24 | 公開日 | 2013-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | 主引用文献 | Hepatitis C virus e2 envelope glycoprotein core structure. Science, 342, 2013
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4OD3
| Crystal structure of human Fab CAP256-VRC26.07, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CAP256-VRC26.07 heavy chain, CAP256-VRC26.07 light chain, ... | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.616 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4ORG
| Crystal structure of human Fab CAP256-VRC26.04, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.04 heavy chain, CAP256-VRC26.04 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-02-11 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.121 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4QNB
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4MYQ
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4ODH
| Crystal structure of human Fab CAP256-VRC26.UCA, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.UCA heavy chain, CAP256-VRC26.UCA light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-10 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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4R73
| Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (endogenous glucose-6-phosphate and mannose-6-phosphate bound) | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, ABC-type Fe3+ transport system, ... | 著者 | Calmettes, C, Tang, C, Sit, B, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
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4QQ1
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2BFG
| crystal structure of beta-xylosidase (fam GH39) in complex with dinitrophenyl-beta-xyloside and covalently bound xyloside | 分子名称: | 2,5-DINITROPHENOL, BETA-XYLOSIDASE, SODIUM ION, ... | 著者 | Czjzek, M, Bravman, T, Henrissat, B, Shoham, Y. | 登録日 | 2004-12-07 | 公開日 | 2005-10-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Enzyme-Substrate Complex Structures of a Gh39 Beta-Xylosidase from Geobacillus Stearothermophilus. J.Mol.Biol., 353, 2005
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2C0A
| Mechanism of the Class I KDPG aldolase | 分子名称: | KHG/KDPG ALDOLASE, PHOSPHATE ION | 著者 | Hutchins, M.J, Fullerton, S.W.B, Toone, E.J, Naismith, J.H. | 登録日 | 2005-08-29 | 公開日 | 2005-09-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Mechanism of the Class I Kdpg Aldolase. Bioorg.Med.Chem., 14, 2006
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2BDL
| Cathepsin K complexed with a pyrrolidine ketoamide-based inhibitor | 分子名称: | (3S)-1-{[(3,5-DIMETHYLISOXAZOL-4-YL)AMINO]CARBONYL}-4,4-DIMETHYLPYRROLIDIN-3-YL{(1S)-1-[1-HYDROXY-2-OXO-2-{[(1R)-1-PHENYLETHYL]AMINO}ETHYL]PENTYL}CARBAMATE, Cathepsin K | 著者 | Shewchuk, L.M. | 登録日 | 2005-10-20 | 公開日 | 2006-03-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
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2BS9
| Native crystal structure of a GH39 beta-xylosidase XynB1 from Geobacillus stearothermophilus | 分子名称: | BETA-XYLOSIDASE, CALCIUM ION | 著者 | Czjzek, M, Bravman, T, Henrissat, B, Shoham, Y. | 登録日 | 2005-05-19 | 公開日 | 2005-10-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Enzyme-Substrate Complex Structures of a Gh39 Beta-Xylosidase from Geobacillus Stearothermophilus. J.Mol.Biol., 353, 2005
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2AUC
| Structure of the Plasmodium MTIP-MyoA complex, a key component of the parasite invasion motor | 分子名称: | Myosin A, Myosin A Tail Interacting Protein | 著者 | Bosch, J, Turley, S, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2005-08-27 | 公開日 | 2006-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2CFX
| Structure of B.subtilis LrpC | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR LRPC | 著者 | Thaw, P, Rafferty, J.B. | 登録日 | 2006-02-24 | 公開日 | 2006-03-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family. Nucleic Acids Res., 34, 2006
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4XRT
| Crystal structure of the di-domain ARO/CYC StfQ from the steffimycin biosynthetic pathway | 分子名称: | FORMIC ACID, StfQ Aromatase/Cyclase | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | 登録日 | 2015-01-21 | 公開日 | 2015-12-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XRW
| Crystal structure of the di-domain ARO/CYC BexL from the BE-7585A biosynthetic pathway | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BexL | 著者 | Tsai, S.C, Caldara-Festin, G.M, Jackson, D.R, Aguilar, S, Patel, A, Nguyen, M, Sasaki, E, Valentic, T.R, Barajas, J.F, Vo, M, Khanna, A, Liu, H.-W. | 登録日 | 2015-01-21 | 公開日 | 2015-12-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZBN
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4Z8D
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4ZMJ
| Crystal Structure of Ligand-Free BG505 SOSIP.664 HIV-1 Env Trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2015-05-04 | 公開日 | 2015-06-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat.Struct.Mol.Biol., 22, 2015
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5AK7
| Structure of wt Porphyromonas gingivalis peptidylarginine deiminase | 分子名称: | 1,2-ETHANEDIOL, ALANINE, ARGININE, ... | 著者 | Kopec, J, Montgomery, A, Shrestha, L, Kiyani, W, Nowak, R, Burgess-Brown, N, Venables, P.J, Yue, W.W. | 登録日 | 2015-03-02 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Crystal Structure of Porphyromonas Gingivalis Peptidylarginine Deiminase: Implications for Autoimmunity in Rheumatoid Arthritis. Ann.Rheum.Dis., 75, 2016
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5BNM
| E. coli FabH with Small Molecule Inhibitor 1 | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, N-{[3'-(hydroxymethyl)biphenyl-4-yl]methyl}benzenesulfonamide, SULFATE ION, ... | 著者 | Kazmirski, S.L, McKinney, D.C. | 登録日 | 2015-05-26 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping. Acs Infect Dis., 2, 2016
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5AK8
| Structure of C351A mutant of Porphyromonas gingivalis peptidylarginine deiminase | 分子名称: | 1,2-ETHANEDIOL, ALANINE, ARGININE, ... | 著者 | Kopec, J, Montgomery, A, Shrestha, L, Kiyani, W, Nowak, R, Burgess-Brown, N, Venables, P.J, Yue, W.W. | 登録日 | 2015-03-02 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal Structure of Porphyromonas Gingivalis Peptidylarginine Deiminase: Implications for Autoimmunity in Rheumatoid Arthritis. Ann.Rheum.Dis., 75, 2016
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