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4ODH

Crystal structure of human Fab CAP256-VRC26.UCA, a potent V1V2-directed HIV-1 neutralizing antibody

Summary for 4ODH
Entry DOI10.2210/pdb4odh/pdb
Related4OCR 4OCS 4OCW 4OD1 4OD3 4ORG
DescriptorCAP256-VRC26.UCA light chain, CAP256-VRC26.UCA heavy chain (3 entities in total)
Functional Keywordsfab, hiv-1, v1v2, cap256, vrc26, immune system
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight49598.92
Authors
Gorman, J.,Doria-Rose, N.A.,Schramm, C.A.,Moore, P.L.,Mascola, J.R.,Shapiro, L.,Morris, L.,Kwong, P.D. (deposition date: 2014-01-10, release date: 2014-02-26, Last modification date: 2023-12-06)
Primary citationDoria-Rose, N.A.,Schramm, C.A.,Gorman, J.,Moore, P.L.,Bhiman, J.N.,Dekosky, B.J.,Ernandes, M.J.,Georgiev, I.S.,Kim, H.J.,Pancera, M.,Staupe, R.P.,Altae-Tran, H.R.,Bailer, R.T.,Crooks, E.T.,Cupo, A.,Druz, A.,Garrett, N.J.,Hoi, K.H.,Kong, R.,Louder, M.K.,Longo, N.S.,McKee, K.,Nonyane, M.,O'Dell, S.,Roark, R.S.,Rudicell, R.S.,Schmidt, S.D.,Sheward, D.J.,Soto, C.,Wibmer, C.K.,Yang, Y.,Zhang, Z.,Sequencing, Nisc Comparative,Mullikin, J.C.,Binley, J.M.,Sanders, R.W.,Wilson, I.A.,Moore, J.P.,Ward, A.B.,Georgiou, G.,Williamson, C.,Abdool Karim, S.S.,Morris, L.,Kwong, P.D.,Shapiro, L.,Mascola, J.R.
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509:55-62, 2014
Cited by
PubMed: 24590074
DOI: 10.1038/nature13036
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.894 Å)
Structure validation

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