1H1W
 
 | | High resolution crystal structure of the human PDK1 catalytic domain | | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | | 著者 | Biondi, R.M, Komander, D, Thomas, C.C, Lizcano, J.M, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2002-07-23 | | 公開日 | 2003-07-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site
Embo J., 21, 2003
|
|
4B0P
 | | Crystal structure of soman-aged human butyrylcholinesterase in complex with methyl 2-(pentafluorobenzyloxyimino)pyridinium | | 分子名称: | 1-(1-methylpyridin-1-ium-2-yl)-N-[[2,3,4,5,6-pentakis(fluoranyl)phenyl]methoxy]methanimine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wandhammer, M, de Koning, M, van Grol, M, Noort, D, Goeldner, M, Nachon, F. | | 登録日 | 2012-07-04 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase
Chem.Biol.Interact, 203, 2013
|
|
3G9K
 | | Crystal structure of Bacillus anthracis transpeptidase enzyme CapD | | 分子名称: | Capsule biosynthesis protein capD, GLUTAMIC ACID | | 著者 | Zhang, R, Wu, R, Richter, S, Anderson, V.J, Missiakas, D, Joachimiak, A. | | 登録日 | 2009-02-13 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Crystal Structure of Bacillus anthracis Transpeptidase Enzyme CapD.
J.Biol.Chem., 284, 2009
|
|
4B55
 | | Crystal Structure of the Covalent Adduct Formed between Mycobacterium marinum Aryalamine N-acetyltransferase and Phenyl vinyl ketone a derivative of Piperidinols | | 分子名称: | 3-hydroxy-1-phenylpropan-1-one, ARYLAMINE N-ACETYLTRANSFERASE NAT | | 著者 | Abuhammad, A, Fullam, E, Lowe, E.D, Staunton, D, Kawamura, A, Westwood, I.M, Bhakta, S, Garner, A.C, Wilson, D.L, Seden, P.T, Davies, S.G, Russell, A.J, Garman, E.F, Sim, E. | | 登録日 | 2012-08-02 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Piperidinols that Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages.
Plos One, 7, 2012
|
|
4AS8
 | | X-ray structure of the cyan fluorescent protein Cerulean cryoprotected with ethylene glycol | | 分子名称: | 1,2-ETHANEDIOL, GREEN FLUORESCENT PROTEIN, MAGNESIUM ION | | 著者 | von Stetten, D, Batot, G, Noirclerc-Savoye, M, Royant, A. | | 登録日 | 2012-04-29 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | | 主引用文献 | Alteration of Fluorescent Protein Spectroscopic Properties Upon Cryoprotection
Acta Crystallogr.,Sect.D, 68, 2012
|
|
4BAI
 | | Mycobacterium tuberculosis Chorismate synthase before exposure to 266 nm UV laser | | 分子名称: | ACETATE ION, CHORISMATE SYNTHASE | | 著者 | Pereira, P.J.B, Royant, A, Panjikar, S, de Sanctis, D. | | 登録日 | 2012-09-14 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures.
J. Struct. Biol., 181, 2013
|
|
4B2N
 | | Latex Oxygenase RoxA | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 70 KDA PROTEIN, HEME C, ... | | 著者 | Seidel, J, Schmitt, G, Hoffmann, M, Jendrossek, D, Einsle, O. | | 登録日 | 2012-07-17 | | 公開日 | 2013-07-24 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the processive rubber oxygenase RoxA from Xanthomonas sp.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
|
|
4B5Y
 | | X-ray structure of the cyan fluorescent protein mTurquoise-GL (K206A mutant) in space group C222(1) | | 分子名称: | GREEN FLUORESCENT PROTEIN | | 著者 | von Stetten, D, Lelimousin, M, Oost, K, Noirclerc-Savoye, M, Gadella, T.W.J, Goedhart, J, Royant, A. | | 登録日 | 2012-08-08 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Influence of the H148G Mutation on Fluorescence Properties of Cyan Fluorescent Proteins
To be Published
|
|
4AY2
 | | Capturing 5' tri-phosphorylated RNA duplex by RIG-I | | 分子名称: | 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Luo, D, Pyle, A.M. | | 登録日 | 2012-06-17 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Structure, 20, 2012
|
|
4B2J
 | | COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS | | 分子名称: | CHLORIDE ION, DODECIN, MAGNESIUM ION, ... | | 著者 | Staudt, H, Hoesl, M, Dreuw, A, Serdjukow, S, Oesterhelt, D, Budisa, N, Wachtveitl, J, Grininger, M. | | 登録日 | 2012-07-16 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Directed Manipulation of a Flavoprotein Photocycle.
Angew.Chem.Int.Ed.Engl., 52, 2013
|
|
3GBV
 | | Crystal structure of a putative LacI transcriptional regulator from Bacteroides fragilis | | 分子名称: | 1,2-ETHANEDIOL, Putative LacI-family transcriptional regulator, SODIUM ION | | 著者 | Syed Ibrahim, B, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-02-20 | | 公開日 | 2009-03-10 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a putative LacI transcriptional regulator from Bacteroides fragilis
To be Published
|
|
1D5W
 | | PHOSPHORYLATED FIXJ RECEIVER DOMAIN | | 分子名称: | SULFATE ION, TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ | | 著者 | Birck, C, Mourey, L, Gouet, P, Fabry, B, Schumacher, J, Rousseau, P, Kahn, D, Samama, J.P. | | 登録日 | 1999-10-12 | | 公開日 | 2000-10-11 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformational changes induced by phosphorylation of the FixJ receiver domain.
Structure Fold.Des., 7, 1999
|
|
1CQF
 | |
1CQP
 | | CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION | | 分子名称: | ANTIGEN CD11A (P180), LOVASTATIN, MAGNESIUM ION | | 著者 | Kallen, J, Welzenbach, K, Ramage, P, Geyl, D, Kriwacki, R, Legge, G, Cottens, S, Weitz-Schmidt, G, Hommel, U. | | 登録日 | 1999-08-10 | | 公開日 | 2000-08-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
J.Mol.Biol., 292, 1999
|
|
1CR5
 | | N-TERMINAL DOMAIN OF SEC18P | | 分子名称: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, SEC18P (RESIDUES 22 - 210) | | 著者 | Babor, S.M, Fass, D. | | 登録日 | 1999-08-13 | | 公開日 | 1999-12-22 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the Sec18p N-terminal domain.
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
4B0Z
 | | Crystal structure of S. pombe Rpn12 | | 分子名称: | 26S PROTEASOME REGULATORY SUBUNIT RPN12, GLYCEROL, MONOTHIOGLYCEROL, ... | | 著者 | Boehringer, J, Riedinger, C, Paraskevopoulos, K, Johnson, E.O.D, Lowe, E.D, Khoudian, C, Smith, D, Noble, M.E.M, Gordon, C, Endicott, J.A. | | 登録日 | 2012-07-06 | | 公開日 | 2012-09-12 | | 最終更新日 | 2012-11-07 | | 実験手法 | X-RAY DIFFRACTION (1.585 Å) | | 主引用文献 | Structural and Functional Characterisation of Rpn12 Identifies Residues Required for Rpn10 Proteasome Incorporation.
Biochem.J., 448, 2012
|
|
2PNW
 | | Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens | | 分子名称: | Membrane-bound lytic murein transglycosylase, SULFATE ION | | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-04-25 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of membrane-bound lytic murein transglycosylase from Agrobacterium tumefaciens.
To be Published
|
|
3GJ2
 | | Photoactivated state of PA-GFP | | 分子名称: | CHLORIDE ION, Green fluorescent protein | | 著者 | Henderson, J.N, Gepshtein, R, Heenan, J.R, Kallio, K, Huppert, D, Remington, S.J. | | 登録日 | 2009-03-07 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of the photoactivatable green fluorescent protein.
J.Am.Chem.Soc., 131, 2009
|
|
4BAN
 | | Thrombin in complex with inhibitor | | 分子名称: | (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R)-2-cyclohexyl-2-[[2-(methylamino)-2-oxidanylidene-ethyl]amino]ethanoyl]azetidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUDIN VARIANT-2, ... | | 著者 | Xue, Y, Musil, D. | | 登録日 | 2012-09-14 | | 公開日 | 2013-01-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
|
|
3GCS
 | | Human P38 MAP kinase in complex with Sorafenib | | 分子名称: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | | 登録日 | 2009-02-22 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.
J.Am.Chem.Soc., 131, 2009
|
|
4AXB
 | | Crystal structure of soman-aged human butyrylcholinesterase in complex with 2-PAM | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wandhammer, M, de Koning, M, Noort, D, Goeldner, M, Nachon, F. | | 登録日 | 2012-06-12 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase
Chem.Biol.Interact, 203, 2013
|
|
4BAK
 | | Thrombin in complex with inhibitor | | 分子名称: | (2S)-N-(4-CARBAMIMIDOYLBENZYL)-1-[(2R)-2-CYCLOHEXYL-2-{[2-OXO-2-(PROPYLAMINO)ETHYL]AMINO}ACETYL]AZETIDINE-2-CARBOXAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUDIN VARIANT-1, ... | | 著者 | Xue, Y, Musil, D. | | 登録日 | 2012-09-14 | | 公開日 | 2013-01-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52, 2013
|
|
4AZ3
 | | crystal structure of cathepsin a, complexed with 15a | | 分子名称: | (3S)-3-({[1-(2-fluorophenyl)-5-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-1H-pyrazol-3-yl]carbonyl}amino)-3-(2-methylphenyl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | | 著者 | Ruf, S, Buning, C, Schreuder, H, Horstick, G, Linz, W, Olpp, T, Pernerstorfer, J, Hiss, K, Kroll, K, Kannt, A, Kohlmann, M, Linz, D, Huebschle, T, Ruetten, H, Wirth, K, Schmidt, T, Sadowski, T. | | 登録日 | 2012-06-22 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Novel Beta-Amino Acid Derivatives as Inhibitors of Cathepsin A.
J.Med.Chem., 55, 2012
|
|
4BB9
 | | Crystal structure of glucokinase regulatory protein complexed to fructose-1-phosphate | | 分子名称: | 1-O-phosphono-beta-D-fructopyranose, CALCIUM ION, GLUCOKINASE REGULATORY PROTEIN | | 著者 | Pautsch, A, Stadler, N, Loehle, A, Lenter, M, Rist, W, Berg, A, Glocker, L, Nar, H, Reinert, D, Heckel, A, Schnapp, G, Kauschke, S.G. | | 登録日 | 2012-09-21 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Crystal Structure of Glucokinase Regulatory Protein.
Biochemistry, 52, 2013
|
|
1D7L
 | | STRUCTURE-FUNCTION CORRELATIONS OF THE REACTION OF REDUCED NICOTINAMIDE ANALOGS WITH P-HYDROXYBENZOATE HYDROXYLASE SUBSTITUTED WITH A SERIES OF 8-SUBSTITUTED FLAVINS | | 分子名称: | 8-DEMETHYL-8-DIMETHYLAMINO-FLAVIN-ADENINE-DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID, ... | | 著者 | Ortiz-Maldonado, M, Gatti, D, Ballou, D.P, Massey, V. | | 登録日 | 1999-10-18 | | 公開日 | 2000-01-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-function correlations of the reaction of reduced nicotinamide analogues with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins.
Biochemistry, 38, 1999
|
|
