2O22
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![BU of 2o22 by Molmil](/molmil-images/mine/2o22) | Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand | 分子名称: | Apoptosis regulator Bcl-2, N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide | 著者 | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | 登録日 | 2006-11-29 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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3E0S
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![BU of 3e0s by Molmil](/molmil-images/mine/3e0s) | Crystal structure of an uncharacterized protein from Chlorobium tepidum | 分子名称: | SULFATE ION, uncharacterized protein | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Powell, A, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-07-31 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of an uncharacterized protein from Chlorobium tepidum To be Published
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1G50
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![BU of 1g50 by Molmil](/molmil-images/mine/1g50) | CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION | 分子名称: | ESTRADIOL, ESTROGEN RECEPTOR | 著者 | Eiler, S, Gangloff, M, Duclaud, S, Moras, D, Ruff, M, Structural Proteomics in Europe (SPINE) | 登録日 | 2000-10-30 | 公開日 | 2002-02-06 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Overexpression, Purification, and Crystal Structure of Native ER alpha LBD Protein Expr.Purif., 22, 2001
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2O6G
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1FWO
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![BU of 1fwo by Molmil](/molmil-images/mine/1fwo) | THE SOLUTION STRUCTURE OF A 35-RESIDUE FRAGMENT FROM THE GRANULIN/EPITHELIN-LIKE SUBDOMAIN OF RICE ORYZAIN BETA (ROB 382-416 (C398S,C399S,C407S,C413S)) | 分子名称: | ORYZAIN BETA CHAIN | 著者 | Tolkatchev, D, Xu, P, Ni, F. | 登録日 | 2000-09-24 | 公開日 | 2001-05-09 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | A peptide derived from the C-terminal part of a plant cysteine protease folds into a stack of two beta-hairpins, a scaffold present in the emerging family of granulin-like growth factors. J.Pept.Res., 57, 2001
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4ANK
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![BU of 4ank by Molmil](/molmil-images/mine/4ank) | Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two T4 binding sites. | 分子名称: | TRANSTHYRETIN | 著者 | Tomar, D, Khan, T, Singh, R.R, Mishra, S, Gupta, S, Surolia, A, Salunke, D.M. | 登録日 | 2012-03-20 | 公開日 | 2012-09-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding Sites. Plos One, 7, 2012
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2O2M
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![BU of 2o2m by Molmil](/molmil-images/mine/2o2m) | Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand | 分子名称: | 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-X | 著者 | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | 登録日 | 2006-11-30 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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1FXJ
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![BU of 1fxj by Molmil](/molmil-images/mine/1fxj) | CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINE 1-PHOSPHATE URIDYLTRANSFERASE | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE | 著者 | Brown, K, Pompeo, F, Dixon, S, Mengin-Lecreulx, D, Cambillau, C, Bourne, Y. | 登録日 | 2000-09-26 | 公開日 | 2000-10-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily. EMBO J., 18, 1999
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2Q7F
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1G25
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![BU of 1g25 by Molmil](/molmil-images/mine/1g25) | SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN TFIIH MAT1 SUBUNIT | 分子名称: | CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1, ZINC ION | 著者 | Gervais, V, Wasielewski, E, Busso, D, Poterszman, A, Egly, J.M, Thierry, J.C, Kieffer, B. | 登録日 | 2000-10-17 | 公開日 | 2000-11-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the N-terminal Domain of the Human TFIIH MAT1 Subunit: New Insights into the RING Finger Family J.Biol.Chem., 276, 2001
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4AC2
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![BU of 4ac2 by Molmil](/molmil-images/mine/4ac2) | CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH LIGAND C-7 | 分子名称: | 2,4-DICHLORO-1-[4-(CHLOROMETHYL)-2-METHOXYPHENOXY]BENZENE, TRANSTHYRETIN | 著者 | Tomar, D, Khan, T, Singh, R.R, Mishra, S, Gupta, S, Surolia, A, Salunke, D.M. | 登録日 | 2011-12-12 | 公開日 | 2012-09-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding Sites. Plos One, 7, 2012
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4ABQ
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![BU of 4abq by Molmil](/molmil-images/mine/4abq) | CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH LIGAND C-1 | 分子名称: | 3-(5-MERCAPTO-1,3,4-OXADIAZOL-2-YL)-PHENOL, TRANSTHYRETIN | 著者 | Tomar, D, Khan, T, Singh, R.R, Mishra, S, Gupta, S, Surolia, A, Salunke, D.M. | 登録日 | 2011-12-10 | 公開日 | 2012-09-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding Sites. Plos One, 7, 2012
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4A31
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![BU of 4a31 by Molmil](/molmil-images/mine/4a31) | CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A PYRAZOLE SULPHONAMIDE LIGAND | 分子名称: | 6-{[2-(4-METHYLPIPERAZIN-1-YL)ETHYL]AMINO}-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)PYRIDINE-3-SULFONAMIDE, GLYCEROL, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, ... | 著者 | Robinson, D.A, Brand, S, Cleghorn, L.A.T, McElroy, S.P, Smith, V.C, Hallyburton, I, Harrison, J.R, Norcross, N.R, Norval, S, Spinks, D, Stojanovski, L, Torrie, L.S, Frearson, J.A, Brenk, R, Fairlamb, A.H, Ferguson, M.A.J, Read, K.D, Wyatt, P.G, Gilbert, I.H. | 登録日 | 2011-09-29 | 公開日 | 2011-12-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. J. Med. Chem., 55, 2012
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3FVD
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![BU of 3fvd by Molmil](/molmil-images/mine/3fvd) | Crystal structure of a member of enolase superfamily from ROSEOVARIUS NUBINHIBENS ISM complexed with magnesium | 分子名称: | MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme | 著者 | Malashkevich, V.N, Rutter, M, Bain, K.T, Lau, C, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-01-15 | 公開日 | 2009-01-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a member of enolase superfamily from ROSEOVARIUS NUBINHIBENS ISM complexed with magnesium to be published
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1GLB
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![BU of 1glb by Molmil](/molmil-images/mine/1glb) | STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL, ... | 著者 | Hurley, J.H, Worthylake, D, Faber, H.R, Meadow, N.D, Roseman, S, Pettigrew, D.W, Remington, S.J. | 登録日 | 1992-10-28 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase. Science, 259, 1993
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2PIF
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![BU of 2pif by Molmil](/molmil-images/mine/2pif) | Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. NorthEast Structural Genomics target PsR181 | 分子名称: | UPF0317 protein PSPTO_5379 | 著者 | Seetharaman, J, Abashidze, M, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-04-13 | 公開日 | 2007-05-01 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of UPF0317 protein PSPTO_5379 from Pseudomonas syringae pv. tomato. To be Published
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3FWR
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2PK8
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![BU of 2pk8 by Molmil](/molmil-images/mine/2pk8) | Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus | 分子名称: | GOLD (I) CYANIDE ION, Uncharacterized protein PF0899 | 著者 | Liu, Z.J, Tempel, W, Chen, L, Shah, A, Lee, D, Clancy-Kelley, L.L, Dillard, B.D, Rose, J.P, Sugar, F.J, Jenny Jr, F.E, Lee, H.S, Izumi, M, Shah, C, Poole III, F.L, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2007-04-17 | 公開日 | 2007-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution. Acta Crystallogr.,Sect.F, 63, 2007
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1GHQ
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![BU of 1ghq by Molmil](/molmil-images/mine/1ghq) | CR2-C3D COMPLEX STRUCTURE | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, COMPLEMENT C3, CR2/CD121/C3D/EPSTEIN-BARR VIRUS RECEPTOR, ... | 著者 | Szakonyi, G, Guthridge, J.M, Li, D, Holers, V.M, Chen, X.S. | 登録日 | 2001-01-11 | 公開日 | 2001-06-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure of complement receptor 2 in complex with its C3d ligand. Science, 292, 2001
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1ESA
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![BU of 1esa by Molmil](/molmil-images/mine/1esa) | DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | 分子名称: | CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION | 著者 | Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. | 登録日 | 1994-02-04 | 公開日 | 1994-04-30 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase. Biochemistry, 33, 1994
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3KB2
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![BU of 3kb2 by Molmil](/molmil-images/mine/3kb2) | Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256 | 分子名称: | GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, SPBc2 prophage-derived uncharacterized protein yorR | 著者 | Forouhar, F, Friedman, D, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Ho, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-20 | 公開日 | 2009-10-27 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target SR256 To be Published
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3G5D
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![BU of 3g5d by Molmil](/molmil-images/mine/3g5d) | Kinase domain of cSrc in complex with Dasatinib | 分子名称: | GLYCEROL, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src | 著者 | Grutter, C, Kluter, S, Rauh, D. | 登録日 | 2009-02-05 | 公開日 | 2009-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc J.Med.Chem., 52, 2009
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3GJ1
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![BU of 3gj1 by Molmil](/molmil-images/mine/3gj1) | Non photoactivated state of PA-GFP | 分子名称: | CHLORIDE ION, Green fluorescent protein, SULFATE ION | 著者 | Henderson, J.N, Gepshtein, R, Heenan, J.R, Kallio, K, Huppert, D, Remington, S.J. | 登録日 | 2009-03-07 | 公開日 | 2009-03-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and mechanism of the photoactivatable green fluorescent protein. J.Am.Chem.Soc., 131, 2009
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2PT5
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![BU of 2pt5 by Molmil](/molmil-images/mine/2pt5) | Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Shikimate kinase | 著者 | Jeyakanthan, J, Nithya, N, Shimada, A, Velmurugan, D, Ebihara, A, Shinkai, A, Kuramitsu, S, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-08 | 公開日 | 2008-05-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure Of Shikimate Kinase (aq_2177) From Aquifex Aeolicus vf5 To be Published
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1EXP
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![BU of 1exp by Molmil](/molmil-images/mine/1exp) | BETA-1,4-GLYCANASE CEX-CD | 分子名称: | BETA-1,4-D-GLYCANASE CEX-CD, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose | 著者 | White, A, Tull, D, Johns, K.L, Withers, S.G, Rose, D.R. | 登録日 | 1996-01-11 | 公開日 | 1997-01-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystallographic observation of a covalent catalytic intermediate in a beta-glycosidase. Nat.Struct.Biol., 3, 1996
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