8TXT
| Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8TY7
| Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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8TXP
| Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ... | 著者 | Lin, T.H, Moore, N, Wilson, I.A. | 登録日 | 2023-08-24 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Maturation of germinal center B cells after influenza virus vaccination in humans. J.Exp.Med., 221, 2024
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3RFJ
| Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | 分子名称: | Internalin B, repeat modules, Variable lymphocyte receptor, ... | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | 登録日 | 2011-04-06 | 公開日 | 2012-03-14 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering Proc.Natl.Acad.Sci.USA, 109, 2012
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7OQ6
| Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | 著者 | Zhang, L, Zhang, S, Bechthold, A, Einsle, O. | 登録日 | 2021-06-02 | 公開日 | 2022-06-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate. Acta Pharm Sin B, 13, 2023
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2MSY
| Solution structure of Hox homeodomain | 分子名称: | Homeobox protein Hox-C9 | 著者 | Kim, H, Park, S, Han, J, Lee, B. | 登録日 | 2014-08-11 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding. Biochim.Biophys.Acta, 1854, 2015
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8FY7
| SARS-CoV-2 main protease in complex with covalent inhibitor | 分子名称: | 3C-like proteinase nsp5, 4-methoxy-N-[(2S)-4-methyl-1-oxo-1-({(2S)-1-[(3S)-2-oxopyrrolidin-3-yl]but-3-en-2-yl}amino)pentan-2-yl]-1H-indole-2-carboxamide | 著者 | Fried, W, Chen, X.S. | 登録日 | 2023-01-25 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease. J.Med.Chem., 66, 2023
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8FY6
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7T3F
| Development of BRD4 inhibitors as arsenicals antidotes | 分子名称: | 4-fluoro-3-methyl-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzene-1-sulfonamide, Bromodomain-containing protein 4, GLYCEROL | 著者 | Wu, M, Yatchang, M, Mathew, B, Zhai, L, Ruiz, P, Bostwick, R, Augelli-Szafran, C.E, Suto, M.J. | 登録日 | 2021-12-07 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals. Bioorg.Med.Chem.Lett., 64, 2022
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4NSQ
| Crystal structure of PCAF | 分子名称: | COENZYME A, Histone acetyltransferase KAT2B | 著者 | Lin, J.Y, Cai, Y.F. | 登録日 | 2013-11-28 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3108 Å) | 主引用文献 | Dimeric structure of p300/CBP associated factor. Bmc Struct.Biol., 14, 2014
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8G6C
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8G8V
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7UYI
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5GSA
| EED in complex with an allosteric PRC2 inhibitor | 分子名称: | Histone-lysine N-methyltransferase EZH2, N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, Polycomb protein EED | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of Nat. Chem. Biol., 13, 2017
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1CN4
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6O98
| Crystal structure of RAR-related orphan receptor C in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor | 分子名称: | 1-(4-{(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]pyrrolidine-1-carbonyl}piperazin-1-yl)ethan-1-one, Nuclear receptor ROR-gamma | 著者 | Sack, J.S. | 登録日 | 2019-03-13 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active ROR gamma t Inverse Agonists. ACS Med Chem Lett, 10, 2019
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8COH
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8COE
| complement C5 in complex with the LCP0195 nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ... | 著者 | Andersen, G.R, Pedersen, D.V. | 登録日 | 2023-02-28 | 公開日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration. Mol.Immunol., 165, 2023
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6JLA
| Crystal structure of a mouse ependymin related protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1 | 著者 | Park, S. | 登録日 | 2019-03-04 | 公開日 | 2020-03-04 | 最終更新日 | 2020-09-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder. Iucrj, 6, 2019
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6JLD
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6PSH
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6PXE
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6PSK
| Crystal structure of the complex between periplasmic domains of antiholin RI and holin T from T4 phage, in P6522 | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Antiholin, ... | 著者 | Kuznetsov, V.B, Krieger, I.V, Sacchettini, J.C. | 登録日 | 2019-07-12 | 公開日 | 2020-06-24 | 最終更新日 | 2020-08-12 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. J.Mol.Biol., 432, 2020
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6PX4
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6JL9
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