7UYI

Crystal structure of the computationally optimized broadly reactive H1 influenza hemagglutinin P1

Summary for 7UYI

Entry DOI	10.2210/pdb7uyi/pdb
Descriptor	COBRA P1 HA, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	hemagglutinin, virus entry, antigenic, viral protein
Biological source	Influenza A virus
Total number of polymer chains	6
Total formula weight	356482.86
Authors	Dzimianski, J.V.,DuBois, R.M. (deposition date: 2022-05-06, release date: 2023-04-19, Last modification date: 2024-05-01)
Primary citation	Dzimianski, J.V.,Han, J.,Sautto, G.A.,O'Rourke, S.M.,Cruz, J.M.,Pierce, S.R.,Ecker, J.W.,Carlock, M.A.,Nagashima, K.A.,Mousa, J.J.,Ross, T.M.,Ward, A.B.,DuBois, R.M. Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine. Commun Biol, 6:454-454, 2023 Cited by PubMed: 37185989 DOI: 10.1038/s42003-023-04793-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation