1I77
| CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ESSEX 6 | 分子名称: | CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Einsle, O, Foerster, S, Mann, K.H, Fritz, G, Messerschmidt, A, Kroneck, P.M.H. | 登録日 | 2001-03-08 | 公開日 | 2001-08-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Spectroscopic investigation and determination of reactivity and structure of the tetraheme cytochrome c3 from Desulfovibrio desulfuricans Essex 6. Eur.J.Biochem., 268, 2001
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1J93
| Crystal Structure and Substrate Binding Modeling of the Uroporphyrinogen-III Decarboxylase from Nicotiana tabacum: Implications for the Catalytic Mechanism | 分子名称: | SULFATE ION, UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Martins, B.M, Grimm, B, Mock, H.-P, Huber, R, Messerschmidt, A. | 登録日 | 2001-05-23 | 公開日 | 2001-10-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum. Implications for the catalytic mechanism J.Biol.Chem., 276, 2001
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1E5Z
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1E5Y
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7B75
| Cryo-EM Structure of Human Thyroglobulin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thyroglobulin, ... | 著者 | Adaixo, R, Righetto, R, Steiner, E.M, Taylor, N.M.I, Stahlberg, H. | 登録日 | 2020-12-09 | 公開日 | 2021-12-29 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of native human thyroglobulin. Nat Commun, 13, 2022
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2L7U
| Structure of CEL-PEP-RAGE V domain complex | 分子名称: | Advanced glycosylation end product-specific receptor, Serum albumin peptide | 著者 | Xue, J, Rai, V, Schmidt, A, Frolov, S, Reverdatto, S, Singer, D, Chabierski, S, Xie, J, Burz, D, Shekhtman, A, Hoffman, R. | 登録日 | 2010-12-23 | 公開日 | 2011-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Advanced glycation end product recognition by the receptor for AGEs. Structure, 19, 2011
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2LMB
| Solution Structure of C-terminal RAGE (ctRAGE) | 分子名称: | Advanced glycosylation end product-specific receptor | 著者 | Rai, V, Maldonado, A.Y, Burz, D.S, Reverdatto, S, Schmidt, A, Shekhtman, A. | 登録日 | 2011-11-29 | 公開日 | 2011-12-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1. J.Biol.Chem., 287, 2012
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6ECR
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6ECP
| The human methylenetetrahydrofolate dehydrogenase/cyclohydrolase (FolD) complexed with NADP and inhibitor LY249543 | 分子名称: | Methylenetetrahydrofolate dehydrogenase cyclohydrolase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Bueno, R.V, Dawson, A, Hunter, W.N. | 登録日 | 2018-08-08 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase-ligand complexes following further refinement. Acta Crystallogr F Struct Biol Commun, 75, 2019
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6ECQ
| The human methylenetetrahydrofolate dehydrogenase/cyclohydrolase (FolD) complexed with NADP and inhibitor LY345899 | 分子名称: | METHYLENETETRAHYDROFOLATE DEHYDROGENASE CYCLOHYDROLASE, N-{4-[(6aR)-3-amino-1,9-dioxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzene-1-carbonyl}-L-glutamic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Bueno, R.V, Dawson, A, Hunter, W.N. | 登録日 | 2018-08-08 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase-ligand complexes following further refinement. Acta Crystallogr F Struct Biol Commun, 75, 2019
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5IIG
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5IIT
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5IJH
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5IIQ
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5IJJ
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5IJP
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6ELW
| High resolution structure of selenocysteine containing human GPX4 | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | 著者 | Kalms, J, Borchert, A, Kuhn, H, Scheerer, P. | 登録日 | 2017-09-29 | 公開日 | 2018-06-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction. Biochim. Biophys. Acta, 1863, 2018
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5U5Q
| 12 Subunit RNA Polymerase II at Room Temperature collected using SFX | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A. | 登録日 | 2016-12-07 | 公開日 | 2017-03-29 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Double-flow focused liquid injector for efficient serial femtosecond crystallography. Sci Rep, 7, 2017
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5TRX
| Room temperature structure of an extradiol ring-cleaving dioxygenase from B.fuscum determined using serial femtosecond crystallography | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (II) ION, ... | 著者 | Kovaleva, E.G, Oberthuer, D, Tolstikova, A, Mariani, V. | 登録日 | 2016-10-27 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Double-flow focused liquid injector for efficient serial femtosecond crystallography Sci. Rep., 7, 2017
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8OU3
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 8d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-fluoranyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Maiwald, S, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU5
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11b | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU4
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11a | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-chloranyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU7
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11d | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methoxy-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU6
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11c | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-methyl-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-21 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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8OU9
| Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11e | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-oxidanyl-benzamide, Cereblon isoform 4, ZINC ION | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | 登録日 | 2023-04-22 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J.Med.Chem., 66, 2023
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