7B75

Cryo-EM Structure of Human Thyroglobulin

Summary for 7B75

Entry DOI	10.2210/pdb7b75/pdb
EMDB information	12073
Descriptor	Thyroglobulin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	thyroglobulin, t3 and t4 hormonogenesis, cryo-em, hormone
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	621041.80
Authors	Adaixo, R.,Righetto, R.,Steiner, E.M.,Taylor, N.M.I.,Stahlberg, H. (deposition date: 2020-12-09, release date: 2021-12-29, Last modification date: 2022-01-26)
Primary citation	Adaixo, R.,Steiner, E.M.,Righetto, R.D.,Schmidt, A.,Stahlberg, H.,Taylor, N.M.I. Cryo-EM structure of native human thyroglobulin. Nat Commun, 13:61-61, 2022 Cited by PubMed: 35013249 DOI: 10.1038/s41467-021-27693-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation