7B75

Cryo-EM Structure of Human Thyroglobulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thyroglobulin	polymer	2768	305069.8	2	UniProt (P01266) Pfam (PF00086) Pfam (PF07699) Pfam (PF00135)	Homo sapiens (Human)	Tg
2	C, D, F, I, J... (C, D, F, I, J...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
3	E, K (E, K)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
4	G, M (G, M)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G81315DD)
5	H, N (H, N)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	2	In PDB GlyTouCan (G42984ZU)
6	AA, BA, CA, DA, O... (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	16	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	610139.7
Branched	Number of molecules	12
	Total formula weight	7362.8
Non-Polymers*	Number of molecules	16
	Total formula weight	3539.3
All*	Total formula weight	621041.8

*Water molecules are not included.