6ECR
The human methylenetetrahydrofolate dehydrogenase/cyclohydrolase (FolD) complexed with NADP
Summary for 6ECR
| Entry DOI | 10.2210/pdb6ecr/pdb |
| Descriptor | methylenetetrahydrofolate dehydrogenase cyclohydrolase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | dehydrogenase, cyclohydrolase, bifunctional protein, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 65727.55 |
| Authors | Bueno, R.V.,Dawson, A.,Hunter, W.N. (deposition date: 2018-08-08, release date: 2019-03-27, Last modification date: 2023-10-11) |
| Primary citation | Bueno, R.,Dawson, A.,Hunter, W.N. An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase-ligand complexes following further refinement. Acta Crystallogr F Struct Biol Commun, 75:148-152, 2019 Cited by PubMed: 30839287DOI: 10.1107/S2053230X18018083 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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